2. Gene
  3. THUMPD2 - THUMP domain containing 2 Gene

THUMPD2 - THUMP domain containing 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 THUMP 域 2

种属: Homo sapiens

同用名: C2orf8

基因 ID: 80745 | 基因类型: protein coding

关于 THUMPD2

Cytogenetic location: 2p22.1 Genomic coordinates (GRCh38): 2:39,736,060-39,779,276 (from NCBI)

This gene has 9 transcripts (splice variants), 193 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 6.9), ovary (RPKM 4.8) and 25 other tissues.

功能概要

预测可启用 tRNA (鸟嘌呤) 甲基转移酶活性。预测参与 tRNA 甲基化。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable tRNA (guanine) methyltransferase activity. Predicted to be involved in tRNA methylation. [provided by Alliance of Genome Resources, Apr 2022]

THUMPD2 基因产物(11)

mRNA Protein Name
NM_001321468.1 NP_001308397.1 THUMP domain-containing protein 2 isoform 2
NM_001321469.1 NP_001308398.1 THUMP domain-containing protein 2 isoform 3
NM_001321470.1 NP_001308399.1 THUMP domain-containing protein 2 isoform 4
NM_001321474.1 NP_001308403.1 THUMP domain-containing protein 2 isoform 5
NM_001321475.1 NP_001308404.1 THUMP domain-containing protein 2 isoform 6
NM_001321477.1 NP_001308406.1 THUMP domain-containing protein 2 isoform 7
NM_001321478.1 NP_001308407.1 THUMP domain-containing protein 2 isoform 7
NM_001321479.1 NP_001308408.1 THUMP domain-containing protein 2 isoform 7
NM_001321480.1 NP_001308409.1 THUMP domain-containing protein 2 isoform 7
NM_001321481.1 NP_001308410.1 THUMP domain-containing protein 2 isoform 7
NM_025264.5 NP_079540.2 THUMP domain-containing protein 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

THUMPD2 蛋白结构

THUMP

THUMP: THUMP domain (180 - 255)

UPF0020

UPF0020: Putative RNA methylase family UPF0020 (274 - 412)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 503 a.a.
蛋白主名 其他名称

THUMP domain-containing protein 2

SAM-dependent methyltransferase

THUMPD2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
THUMPD2 Q9BTF0 TRMT112 Homo sapiens Q9UI30
Confocal
34948388
种属内
THUMPD2 Q9BTF0 TRMT112 Homo sapiens Q9UI30
Anti Tag CoIP
34948388
种属内
THUMPD2 Q9BTF0 WFS1 Homo sapiens O76024
Validated Y2H
32814053
种属内
THUMPD2 Q9BTF0 WFS1 Homo sapiens O76024
Y2H Array
32814053
种属内
THUMPD2 Q9BTF0 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Gingival Fibromatosis

Hereditary Gingival Fibromatosis

Hereditary Gingival Hyperplasia

Autosomal Dominant Gingival Fibromatosis

Autosomal Dominant Gingival Hyperplasia

Fibromatosis, Gingival, Hereditary

Fibromatosis, Gingival
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14509 THUMPD2 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus THUMPD2 VGNC VGNC:66179
Bos taurus THUMPD2 VGNC VGNC:35854
Mus musculus THUMPD2 MGD MGI:1919417
Canis familiaris THUMPD2 VGNC VGNC:47361
Macaca mulatta THUMPD2 VGNC VGNC:78384
Rattus norvegicus THUMPD2 RGD RGD:1306878
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z