2. Gene
  3. SETD7 - SET domain containing 7, histone lysine methyltransferase Gene

SETD7 - SET domain containing 7, histone lysine methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 SET 结构域 7，组蛋白赖氨酸甲基转移酶

种属: Homo sapiens

同用名: KMT7; SET7; SET9; SET7/9

基因 ID: 80854 | 基因类型: protein coding

关于 SETD7

Cytogenetic location: 4q31.1 Genomic coordinates (GRCh38): 4:139,492,974-139,556,219 (from NCBI)

This gene has 7 transcripts (splice variants), 194 orthologues and 7 paralogues. Ubiquitous expression in fat (RPKM 22.9), prostate (RPKM 16.7) and 24 other tissues.

功能概要

启用组蛋白-赖氨酸 N-甲基转移酶活性和 p53 结合活性。参与肽基-赖氨酸二甲基化和肽基-赖氨酸单甲基化。在对 DNA 损伤刺激和异染色质组织的细胞反应的上游或内部起作用。位于染色体和核仁中。 [由基因组资源联盟提供，2022 年 4 月]

Enables histone-lysine N-methyltransferase activity and p53 binding activity. Involved in peptidyl-lysine dimethylation and peptidyl-lysine monomethylation. Acts upstream of or within cellular response to DNA damage stimulus and heterochromatin organization. Located in chromosome and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

SETD7 基因产物(3)

mRNA Protein Name
NM_001306199.2 NP_001293128.1 histone-lysine N-methyltransferase SETD7 isoform 2
NM_001306200.2 NP_001293129.1 histone-lysine N-methyltransferase SETD7 isoform 3
NM_030648.4 NP_085151.1 histone-lysine N-methyltransferase SETD7 isoform 1

SETD7 蛋白结构

MORN

MORN: MORN repeat (19 - 34)

MORN

MORN: MORN repeat (36 - 58)

MORN

MORN: MORN repeat (60 - 81)

MORN

MORN: MORN repeat (106 - 127)

SET

SET: SET domain (229 - 336)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
蛋白主名 其他名称

histone-lysine N-methyltransferase SETD7

H3-K4-HMTase SETD7

重组 SETD7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76062 SETD7 Protein, Human (His) Q8WTS6/NP_085151.1 (D2-K366) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18627A PFI-2 hydrochloride Inhibitor 99.52% 否
HY-13807 UNC0646 Inhibitor 99.82% 否
HY-148817 WDR5-0102 Inhibitor 97.02% 否
HY-18627 PFI-2 Inhibitor / 否
HY-110196 (S)-PFI-2 hydrochloride / 否
HY-156455 SETD7-IN-1 Inhibitor / 否
HY-RS12747 SETD7 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SETD7 VGNC VGNC:46058
Rattus norvegicus SETD7 RGD RGD:1586346
Mus musculus SETD7 MGD MGI:1920501
Bos taurus SETD7 VGNC VGNC:34497
Felis catus SETD7 VGNC VGNC:65046
Macaca mulatta SETD7 VGNC VGNC:77348
Others SETD7 NCBI
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