HDAC10 - histone deacetylase 10 Gene

中文名称：组蛋白脱乙酰酶 10

种属: Homo sapiens

同用名: HD10

关于 HDAC10

功能概要

该基因编码的蛋白质属于组蛋白去乙酰化酶家族，其成员使核心组蛋白 N 末端部分的赖氨酸残基脱乙酰化。组蛋白去乙酰化调节染色质结构，并在转录调控、细胞周期进程和发育事件中发挥重要作用。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 8 月]

The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]