1. Cell Cycle/DNA Damage Epigenetics
  2. HDAC
  3. (S)-Trichostatin A

(S)-Trichostatin A  (Synonyms: (S)-TSA)

目录号: HY-15144B
产品使用指南

(S)-Trichostatin A ((S)-TSA) 是一种 HDAC6 选择性抑制剂,对斑马鱼 HDAC6 和人 HDAC6IC50 值分别为 9.88 nM和 11.1 nM。(S)-Trichostatin A 弱抑制其他人 HDAC

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(S)-Trichostatin A Chemical Structure

(S)-Trichostatin A Chemical Structure

CAS No. : 122292-85-7

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Other Forms of (S)-Trichostatin A:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(S)-Trichostatin A ((S)-TSA) is a HDAC6-selective inhibitor with IC50s of 9.88 nM and 11.1 nM for Zebrafish HDAC6 and Human HDAC6, respectively. (S)-Trichostatin A weakly inhibits other human HDACs[1].

IC50 & Target[1]

hHDAC6

11.1 nM (IC50)

Zebrafish HDAC6

9.88 nM (IC50)

hHDAC1

206.3 nM (IC50)

hHDAC2

612.65 nM (IC50)

hHDAC3

320.8 nM (IC50)

hHDAC4

6341 nM (IC50)

hHDAC5

6325 nM (IC50)

hHDAC7

1823.5 nM (IC50)

hHDAC8

312.2 nM (IC50)

hHDAC9

4824 nM (IC50)

hHDAC10

403.35 nM (IC50)

hHDAC11

2684 nM (IC50)

分子量

302.37

Formula

C17H22N2O3

CAS 号
中文名称

(-)-曲古柳菌素A

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(S)-Trichostatin A 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(S)-Trichostatin A
目录号:
HY-15144B
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