CARD6 - caspase recruitment domain family member 6 Gene

中文名称：胱天蛋白酶招募域家族成员 6

种属: Homo sapiens

同用名: CINCIN1

关于 CARD6

功能概要

该基因编码的蛋白质包含半胱天冬酶募集结构域 (CARD) ，这是一种反平行的六螺旋束，可介导同型蛋白质-蛋白质相互作用。编码的蛋白质是一种微管相关蛋白，已被证明与受体相互作用蛋白激酶相互作用，并积极调节信号转导通路，这些通路会聚在诱导型转录因子 NF-kB 的激活上。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein that contains a Caspase recruitment domain (CARD), an antiparallel six-helical bundle that mediates homotypic protein-protein interactions. The encoded protein is a microtubule-associated protein that has been shown to interact with receptor-interacting protein kinases and positively modulate signal transduction pathways converging on activation of the inducible transcription factor NF-kB. [provided by RefSeq, Jul 2008]