2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel Sodium Channel
  4. Huwentoxin I

Huwentoxin I  (Synonyms: HWTX-I)

目录号: HY-P5179
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摩尔计算器

Huwentoxin I (HWTX-I) 是一种肽毒素，可抑制电压门控钠通道和 N 型钙通道。Huwentoxin I 抑制大鼠海马和蟑螂背侧不配对中位 (DUM) 神经元的钠离子通道，IC50 值分别为 66.1 和 4.80 nM。

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Custom Peptide Synthesis

Huwentoxin I Chemical Structure

Huwentoxin I Chemical Structure

CAS No. : 769973-37-7

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Huwentoxin I 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC50 values of 66.1 and 4.80 nM, respectively[1].

分子量

3750.36

Formula

C161H246N48O44S6
CAS 号
Sequence

Ala-Cys-Lys-Gly-Val-Phe-Asp-Ala-Cys-Thr-Pro-Gly-Lys-Asn-Glu-Cys-Cys-Pro-Asn-Arg-Val-Cys-Ser-Asp-Lys-His-Lys-Trp-Cys-Lys-Trp-Lys-Leu (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
Sequence Shortening

ACKGVFDACTPGKNECCPNRVCSDKHKWCKWKL (Disulfide bridge: Cys2-Cys17; Cys9-Cys22; Cys16-Cys29)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Huwentoxin I 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Huwentoxin I769973-37-7HWTX-ICalcium ChannelSodium ChannelCa2+ channelsCa channelsNa channelsNa+ channelssodium channel inhibitorcalcium channel inhibitorInhibitorinhibitorinhibit

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