1. Cytoskeleton
  2. Integrin
  3. Lys-Gln-Ala-Gly-Asp-Val

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) 是纤维蛋白原 γ 链序列 (fibrinogen γ-chain) 中最靠羧基末端的六个氨基酸。Lys-Gln-Ala-Gly-Asp-Val 是一种细胞粘附肽,其通过 α2bβ3 整合素介导细胞粘附。Lys-Gln-Ala-Gly-Asp-Val 是一种有效的平滑肌细胞 (SMCs) 粘附配体。

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Custom Peptide Synthesis

Lys-Gln-Ala-Gly-Asp-Val Chemical Structure

Lys-Gln-Ala-Gly-Asp-Val Chemical Structure

CAS No. : 80755-87-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lys-Gln-Ala-Gly-Asp-Val (KQAGDV) is the six most carboxyl-terminal amino acids in the fibrinogen γ-chain sequence. Lys-Gln-Ala-Gly-Asp-Val is a cell adhesion peptide which is mediated through the α2bβ3 integrin. Lys-Gln-Ala-Gly-Asp-Val is a potent adhesion ligand for smooth muscle cells (SMCs)[1][2].

体外研究
(In Vitro)

Lys-Gln-Ala-Gly-Asp-Val (2 nM) improves smooth muscle cell adhesion and growth on polymers[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

616.66

Formula

C25H44N8O10

CAS 号
Sequence Shortening

KQAGDV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Lys-Gln-Ala-Gly-Asp-Val 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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