2. Academic Validation
  3. Molecular basis of methyl-salicylate-mediated plant airborne defence

Molecular basis of methyl-salicylate-mediated plant airborne defence

  • Nature. 2023 Sep 13. doi: 10.1038/s41586-023-06533-3.
Qian Gong # 1 2,  Yunjing Wang # 1 2,  Linfang He 1 2,  Fan Huang 1 2,  Danfeng Zhang 1 2,  Yan Wang 1 2,  Xiang Wei 1,  Meng Han 3,  Haiteng Deng 3,  Lan Luo 4,  Feng Cui 4,  Yiguo Hong 5 6 7 8,  Yule Liu 9 10
Affiliations

Affiliations

  • 1 MOE Key Laboratory of Bioinformatics and Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China.
  • 2 Tsinghua-Peking Center for Life Sciences, Beijing, China.
  • 3 Protein Research Technology Center, Protein Chemistry and Omics Platform, School of Life Sciences, Tsinghua University, Beijing, China.
  • 4 State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • 5 State Key Laboratory of North China Crop Improvement and Regulation and College of Horticulture, Hebei Agricultural University, Baoding, China.
  • 6 Research Centre for Plant RNA Signaling, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
  • 7 School of Life Sciences, University of Warwick, Coventry, UK.
  • 8 School of Science and the Environment, University of Worcester, Worcester, UK.
  • 9 MOE Key Laboratory of Bioinformatics and Center for Plant Biology, School of Life Sciences, Tsinghua University, Beijing, China. yuleliu@mail.tsinghua.edu.cn.
  • 10 Tsinghua-Peking Center for Life Sciences, Beijing, China. yuleliu@mail.tsinghua.edu.cn.
  • # Contributed equally.
PMID: 37704724 DOI: 10.1038/s41586-023-06533-3
Abstract

Aphids transmit viruses and are destructive crop pests1. Plants that have been attacked by aphids release volatile compounds to elicit airborne defence (AD) in neighbouring Plants2-5. However, the mechanism underlying AD is unclear. Here we reveal that methyl-salicylate (MeSA), salicylic acid-binding protein-2 (SABP2), the transcription factor NAC2 and salicylic acid-carboxylmethyltransferase-1 (SAMT1) form a signalling circuit to mediate AD against aphids and viruses. Airborne MeSA is perceived and converted into salicylic acid by SABP2 in neighbouring Plants. Salicylic acid then causes a signal transduction cascade to activate the NAC2-SAMT1 module for MeSA biosynthesis to induce plant anti-aphid immunity and reduce virus transmission. To counteract this, some aphid-transmitted viruses encode helicase-containing proteins to suppress AD by interacting with NAC2 to subcellularly relocalize and destabilize NAC2. As a consequence, Plants become less repellent to aphids, and more suitable for aphid survival, infestation and viral transmission. Our findings uncover the mechanistic basis of AD and an aphid-virus co-evolutionary mutualism, demonstrating AD as a potential bioinspired strategy to control aphids and viruses.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z