1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. mGluR2 modulator 3

mGluR2 modulator 3 (compound 1) 是一种有效的 mGluR2 正向变构调节剂,EC50 为 0.87 μM。mGluR2 modulator 3 在精神疾病模型中具有体内活性,如在小鼠中甲基苯丙胺诱导的多动症和 Mescaline 诱导的抓挠症。

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mGluR2 modulator 3 Chemical Structure

mGluR2 modulator 3 Chemical Structure

CAS No. : 1004614-58-7

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  • 生物活性

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生物活性

mGluR2 modulator 3 (compound 1) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.87 μM. mGluR2 modulator 3 has activity in psychosis disease models such as methamphetamine-induced hyperactivity and mescaline-induced scratching in mice[1].

IC50 & Target[1]

mGluR2

0.87 μM (EC50)

分子量

335.44

Formula

C21H25N3O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

mGluR2 modulator 3 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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mGluR2 modulator 3
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