1. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  2. Cathepsin Deubiquitinase
  3. N-Ethylmaleimide-d5

N-Ethylmaleimide-d5  (Synonyms: N-乙基马来酰亚胺 d5; NEM-d5)

目录号: HY-D0843S 纯度: 99.35%
COA 产品使用指南

N-Ethylmaleimide-d5 是 N-Ethylmaleimide 的氘代物。N-Ethylmaleimide (NEM),烷基化自由巯基的试剂, 是一种半胱氨酸蛋白酶抑制剂。N-Ethylmaleimide 特异性抑制线粒体中的磷酸盐转运。N-Ethylmaleimide 同样也是一种去泛素化酶 (deubiquitinating enzyme) 抑制剂。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

N-Ethylmaleimide-d<sub>5</sub> Chemical Structure

N-Ethylmaleimide-d5 Chemical Structure

CAS No. : 360768-37-2

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥1900
In-stock
5 mg ¥5350
In-stock
10 mg ¥8600
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of N-Ethylmaleimide-d5:

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Ethylmaleimide-d5 is the deuterium labeled N-Ethylmaleimide. N-Ethylmaleimide (NEM), a reagent that alkylates free sulfhydryl groups, is a cysteine protease inhibitor[1]. N-ethylmaleimide specific inhibits phosphate transport in mitochondria[2]. N-Ethylmaleimide is also a deubiquitinating enzyme inhibitor[3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

130.16

Formula

C6H2D5NO2

CAS 号
性状

固体

颜色

White to off-white

中文名称

N-乙基马来酰亚胺 d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 100 mg/mL (768.29 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 7.6829 mL 38.4143 mL 76.8285 mL
5 mM 1.5366 mL 7.6829 mL 15.3657 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.6829 mL 38.4143 mL 76.8285 mL 192.0713 mL
5 mM 1.5366 mL 7.6829 mL 15.3657 mL 38.4143 mL
10 mM 0.7683 mL 3.8414 mL 7.6829 mL 19.2071 mL
15 mM 0.5122 mL 2.5610 mL 5.1219 mL 12.8048 mL
20 mM 0.3841 mL 1.9207 mL 3.8414 mL 9.6036 mL
25 mM 0.3073 mL 1.5366 mL 3.0731 mL 7.6829 mL
30 mM 0.2561 mL 1.2805 mL 2.5610 mL 6.4024 mL
40 mM 0.1921 mL 0.9604 mL 1.9207 mL 4.8018 mL
50 mM 0.1537 mL 0.7683 mL 1.5366 mL 3.8414 mL
60 mM 0.1280 mL 0.6402 mL 1.2805 mL 3.2012 mL
80 mM 0.0960 mL 0.4802 mL 0.9604 mL 2.4009 mL
100 mM 0.0768 mL 0.3841 mL 0.7683 mL 1.9207 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
N-Ethylmaleimide-d5
目录号:
HY-D0843S
需求量: