1. Protein Tyrosine Kinase/RTK
  2. PDGFR
  3. Olaratumab

Olaratumab  (Synonyms: IMC-3G3; LY3012207)

目录号: HY-P9922 纯度: ≥95.0%
COA

Olaratumab(IMC-3G3; LY3012207) 是一种抗血小板衍生生长因子受体α (PDGFRα)的人单克隆 IgG1 抗体,具有抗肿瘤活性。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

我们将采用定制合成服务的方式为您快速提供所需产品和技术服务

Olaratumab Chemical Structure

Olaratumab Chemical Structure

CAS No. : 1024603-93-7

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥4500
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products

查看 PDGFR 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Olaratumab (IMC-3G3; LY3012207) is an anti-platelet-derived growth factor receptor alpha (PDGFRα) human monoclonal IgG1 antibody with antitumor activity[1].

体外研究
(In Vitro)

IMC-3G3 (100 μg/mL, 72 h) 阻断了SKOV3-ip1 细胞的 PDGFRα 磷酸化。并且 IMC-3G3 和多西他赛联合处理时在 SKOV3-ip1 和 HeyA8 两种细胞系中显著诱导了凋亡[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

IMC-3G3 (i.p., 40 mg/kg, three times per week, 6 weeks)在 SKOV3-ip1 荷瘤小鼠中,与对照组相比,IMC-3G3 单独处理没有明显的抗肿瘤作用,而在 HeyA8 荷瘤小鼠中,IMC-3G3 单药处理与对照组相比显示出显著的抗肿瘤作用,肿瘤减少率为 62%[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: ≥95.0%

参考文献

Olaratumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Olaratumab
目录号:
HY-P9922
需求量: