2. Immunology/Inflammation
  3. Interleukin Related
  4. Oxelumab

Oxelumab  (Synonyms: R 4930; huMAb OX 40L; Ro 49-89991)

目录号: HY-P99408 纯度: ≥95.0%
COA

摩尔计算器

Oxelumab (R 4930) 是一种靶向 OX40 配体 (OX40L) 的人单克隆抗体。Oxelumab 可用于哮喘的研究。

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Oxelumab Chemical Structure

Oxelumab Chemical Structure

CAS No. : 1186098-83-8

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规格 价格 是否有货 数量
1 mg ￥1300
In-stock
5 mg ￥3800
In-stock
10 mg ￥6000
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Oxelumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oxelumab (R 4930) is a human monoclonal antibody against the OX40 ligand (OX40L). Oxelumab can be used for the research of asthma[1].

体外研究
(In Vitro)

Oxelumab (10 μg/mL；3 天) 抑制 NK 细胞的增殖[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Oxelumab 相关抗体:

Cell Proliferation Assay[2]

Cell Line: Natural Killer (NK) cell lines
Concentration: 10 μg/mL
Incubation Time: 3 days
Result: Inhibited cell proliferation of NK cells.
体内研究
(In Vivo)

Oxelumab (5 和 30 mg/kg；腹腔注射，每天一次，共两次) 影响 IL-6 的浓度和脾人效应记忆 T 细胞和开关 B 细胞的频率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: NSG mice with PBMCs from UC patients with simple clinical colitis activity index (SCCAI)[1]
Dosage: 5 and 30 mg/kg
Administration: Intraperitoneal injectionon; 5 and 30 mg/kg, once daily, on days 6 and 13
Result: Reversed the ethanol-induced colon dilated and the lost of distinct pattern of pellets. Decreased the level of IL-6 and increased the concentrations of glutamic acid. Reduced frequencies of splenic human effector memory T cells and switched B cells.
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Oxelumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxelumab1186098-83-8R 4930 huMAb OX 40L Ro 49-89991R4930R-4930Interleukin RelatedILAsthmaNKIL-6T cellB cellmiceInhibitorinhibitorinhibit

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