2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Pembrolizumab (anti-PD-1)

Pembrolizumab (anti-PD-1) 

目录号: HY-P9902A 纯度: 99.90%
COA

摩尔计算器

Pembrolizumab (anti-PD-1) 是一种人源化 IgG4 抗体和 PD-1 抑制剂。Pembrolizumab 可产生 PD-1 阻断，防止 PD-L1、PD-L2 连接 PD-1。这避免了 T 细胞对正常表达 PD-1 细胞的调节失控。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Pembrolizumab (anti-PD-1) Chemical Structure

Pembrolizumab (anti-PD-1) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥2000
In-stock
5 mg ￥5700
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Customer Review

Pembrolizumab (anti-PD-1) 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 2 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pembrolizumab (anti-PD-1) is a humanized IgG4 antibody and PD-1 inhibitor. Pembrolizumab produces PD-1 blockade, preventing PD-L1 and PD-L2 from connecting to PD-1. This avoids the uncontrolled regulation of T cells on cells that normally express PD-1[1][2].

体外研究
(In Vitro)

去铁胺 (Df) 螯合 Pembrolizumab，不会阻碍或改变 Pembrolizumab 与 CD4+ 和 CD8+ T 细胞的结合亲和力或特异性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Pembrolizumab (anti-PD-1) 相关抗体:
体内研究
(In Vivo)

实验证实，89Zr-Df-Pembrolizumab 具有 740 mBq/mg 抗体的特异性活性。其中，mBq 是放射性活度的单位，用于衡量放射性衰变[2]。
正电子发射体 89Zr 标记的去铁胺 (Df)-Pembrolizumab，经过 PET 成像，能够动态追踪其生物分布。结果显示，Pembrolizumab 在血液循环中保持稳定，并在肝和脾组织中积累最多。且在小鼠和大鼠均表现出相似的生物分布和药代动力学[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 99.90%

COA (172 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Pembrolizumab (anti-PD-1) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pembrolizumab (anti-PD-1)PD-1/PD-L1PD-1/Programmed death-ligand 189Zrdosimetrypembrolizumabpositron emission tomographyPETInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Pembrolizumab (anti-PD-1)
目录号：
HY-P9902A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z