2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Petiline

Petiline 是一种甾体生物碱，发现于 Petilium raddeanum 中，是 M 胆碱能受体 (M cholinergic receptors) 的选择性拮抗剂。Petiline 通过竞争性阻断 M 胆碱能受体发挥抗胆碱能作用 (例如，减少迷走神经对心脏的影响)，还具有中枢兴奋、强心和解痉作用。Petiline 有望用于胆碱能系统相关疾病 (如心律失常、肠痉挛) 的研究。

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Petiline

Petiline Chemical Structure

CAS No. : 26989-18-4

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Petiline 相关抗体

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Petiline is a steroidal alkaloid found in Petilium raddeanum, acting as a selective antagonist of M cholinergic receptors. Petiline exerts anticholinergic effects (e.g., reducing vagal influence on the heart) by competitively blocking M cholinergic receptors, and also has central excitatory, cardiotonic, and spasmolytic activities. Petiline is promising for research of cholinergic system-related diseases (e.g., arrhythmia, intestinal spasm) [1].

分子量

413.64

Formula

C27H43NO2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Petiline 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Petiline26989-18-4mAChRMuscarinic acetylcholine receptorsteroidal alkaloidanticholinergic effectscholinergic system-related diseasesInhibitorinhibitorinhibit

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