1. Stem Cell/Wnt TGF-beta/Smad
  2. PKA
  3. PKI (14-24)amide

PKI (14-24)amide 是一种有效的 PKA 抑制剂。PKI (14-24)amide 在细胞匀浆中强烈抑制环 AMP 依赖性蛋白激酶活性。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 PKI (14-24)amide TFA 通常具有更好的水溶性和稳定性。

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Custom Peptide Synthesis

PKI (14-24)amide Chemical Structure

PKI (14-24)amide Chemical Structure

CAS No. : 100853-61-0

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     可免费申领三个不同产品的试用装。

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规格 是否有货
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100 mg   询价  
250 mg   询价  

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PKI (14-24)amide 的其他形式现货产品:

Customer Review

Other Forms of PKI (14-24)amide:

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PKI (14-24)amide is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate[1][2].

体外研究
(In Vitro)

PKI (14-24)amide 不抑制环 AMP 诱发的皂素渗透细胞淀粉酶释放[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1251.36

Formula

C49H86N24O15

CAS 号
Sequence Shortening

GRTGRRNAIHD-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

PKI (14-24)amide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PKI (14-24)amide
目录号:
HY-P3929
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