1. Anti-infection
  2. HIV CMV
  3. PMEDAP

PMEDAP 是人类免疫缺陷病毒 (HIV) 复制的有效抑制剂。PMEDAP 具有抗小鼠巨细胞病毒 (MCMV) 活性。PMEDAP 是莫罗尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂。

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PMEDAP Chemical Structure

PMEDAP Chemical Structure

CAS No. : 113852-41-8

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality[1][2].

体内研究
(In Vivo)

PMEDAP (0.25-5 mg/kg; IP; daily; starting on the day of MSV-infected and continuing for an additional four days) causes a dose-dependent suppression of tumor formation and mortality in newborn mice inoculated with MSV[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Three-week-old male NMRI mice[1]
Dosage: 0.25 mg/kg, 1 mg/kg, 5 mg/kg
Administration: IP; daily; starting on the day of infection and continuing for an additional four days
Result: Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.
分子量

288.20

Formula

C8H13N6O4P

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

0.1 M NaOH 中的溶解度 : 14.29 mg/mL (49.58 mM; 超声助溶; 碱性条件溶解 (NaOH 调节,pH≈11))

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.4698 mL 17.3491 mL 34.6981 mL
5 mM 0.6940 mL 3.4698 mL 6.9396 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥98.0%

参考文献

PMEDAP 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
0.1 M NaOH 1 mM 3.4698 mL 17.3491 mL 34.6981 mL 86.7453 mL
5 mM 0.6940 mL 3.4698 mL 6.9396 mL 17.3491 mL
10 mM 0.3470 mL 1.7349 mL 3.4698 mL 8.6745 mL
15 mM 0.2313 mL 1.1566 mL 2.3132 mL 5.7830 mL
20 mM 0.1735 mL 0.8675 mL 1.7349 mL 4.3373 mL
25 mM 0.1388 mL 0.6940 mL 1.3879 mL 3.4698 mL
30 mM 0.1157 mL 0.5783 mL 1.1566 mL 2.8915 mL
40 mM 0.0867 mL 0.4337 mL 0.8675 mL 2.1686 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PMEDAP
目录号:
HY-106382
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