2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. Transmembrane Glycoprotein ADC Antibody
  4. Polatuzumab

Polatuzumab  (Synonyms: 维泊妥珠单抗)

目录号: HY-P99042 纯度: 99.69%
COA 技术支持

Polatuzumab 是一种靶向 B 细胞表面的 CD79b 单克隆抗体。Polatuzumab 可用于合成 ADC Polatuzumab Vedotin (HY-132253)，具有抗肿瘤的活性。

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CAS No. : 2279068-37-8

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规格 价格 是否有货 数量
1 mg ￥1500
In-stock
5 mg ￥3900
In-stock
10 mg ￥5700
In-stock
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100 mg   询价  

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Polatuzumab 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity[1].

同型

Human IgG1 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

CD79B
体外研究
(In Vitro)

Polatuzumab Vedotin 由人源化抗 CD79b 单克隆抗体与合成微管破坏剂 MMAE (HY-15162) 通过可裂解肽连接子连接而成，可用于弥漫性大 B 细胞淋巴瘤 (DLBCL) 的研究[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Polatuzumab 相关抗体:
Clinical Trial
基因 ID

974  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

145.5 kDa

CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

维泊妥珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Flow Cytometry analysis of Raji cells labelling CD79B (red) with Polatuzumab (anti-CD79B) (HY-P99042). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
  • Immobilized CD79B Protein, Human (HY-P70541) can bind Polatuzumab, with the EC50 is 1.037 ng/mL.
纯度 & 产品资料

纯度: 99.69%

COA (265 KB) SDS-PAGE (88 KB) SEC-HPLC (223 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Polatuzumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polatuzumab2279068-37-8维泊妥珠单抗Transmembrane GlycoproteinADC Antibodymonoclonal antibodytargets CD79bADCDLBCLInhibitorinhibitorinhibit

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