1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens
  3. TNF Superfamily Epithelial cell CD Proteins Endothelial cell CD Proteins
  4. TNF Receptor Superfamily
  5. TNF-R2/CD120b

TNF-R2/CD120b  (肿瘤坏死因子受体 2)

TNFRII (TNFRSF1B) 蛋白具有与肿瘤坏死因子-α (TNF-α) 高度结合的能力。TNFRII 具有促凋亡作用。TNFRII 招募 TRAF2,诱导基因表达并与 TNFRI 进行密集串扰。TNFRII 选择性地增强死亡受体 TNFRII 诱导的细胞凋亡。

TNFRII (TNFRSF1B) protein has a high ability to bind with tumor necrosis factor-alpha (TNF-α). TNFRII has pro-apoptotic function. TNFRII recruits TRAF2, induces gene expression and intensively crosstalks with TNF-R1. TNFRII selectively enhances the induction of apoptosis by the death receptor TNFRI[1].

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