1. Anti-infection Neuronal Signaling GPCR/G Protein
  2. Parasite 5-HT Receptor
  3. (R)-Praziquantel-d11

(R)-Praziquantel-d11  (Synonyms: (R)-吡喹酮 D11)

目录号: HY-126057S 纯度: ≥99.0%
COA 产品使用指南

(R)-Praziquantel-d11 是 (R)-Praziquantel 的氘代物。(R)-Praziquantel 是 Praziquantel 的活性对映体,是一种人 5-HT2B 受体的部分激动剂。(R)-Praziquantel 用作驱虫药,抗血吸虫。

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(R)-Praziquantel-d<sub>11</sub> Chemical Structure

(R)-Praziquantel-d11 Chemical Structure

CAS No. : 1399880-38-6

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5 mg ¥9500
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-Praziquantel-d11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].

IC50 & Target[1]

5-HT2B Receptor

 

Schistosome

 

Antischistosomal

 

体外研究
(In Vitro)

(R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

323.47

Formula

C19H13D11N2O2

CAS 号
性状

固体

颜色

White to off-white

中文名称

(R)-吡喹酮 d11

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
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