1. Membrane Transporter/Ion Channel Apoptosis
  2. Proton Pump Apoptosis
  3. Rabeprazole-d4

Rabeprazole-d4  (Synonyms: LY307640-d4)

目录号: HY-B0656S 纯度: ≥95.0%
COA 产品使用指南

Rabeprazole-d4 是 Rabeprazole 的一种氘代化合物。Rabeprazole 是一种二代质子泵抑制剂 (pump inhibitor, PPI),不可逆地抑制胃 H+/K+-ATPase。Rabeprazole 诱导细胞凋亡 (apoptosis)。Rabeprazole 也抑制尿苷核苷核糖水解酶 (UNH) ,IC50 为 0.3 μM。Rabeprazole 可用于胃溃疡和胃食管反流的研究。

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Rabeprazole-d<sub>4</sub> Chemical Structure

Rabeprazole-d4 Chemical Structure

CAS No. : 934295-48-4

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1 mg ¥1500
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Other Forms of Rabeprazole-d4:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rabeprazole-d4 is a deuterium labeled Rabeprazole. Rabeprazole is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole induces apoptosis. Rabeprazole acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

IC50 & Target

Pump inhibitor (PPI); UNH[1]
H+/K+-ATPase; Apoptosis[2]

分子量

363.47

Formula

C18H17D4N3O3S

CAS 号
性状

固体

颜色

White to off-white

中文名称

雷贝拉唑 d4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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