2. Others Immunology/Inflammation GPCR/G Protein Neuronal Signaling
  3. Histamine Receptor Isotope-Labeled Compounds
  4. Ranitidine-d6

Ranitidine-d6  (Synonyms: 雷尼替丁-d6)

目录号: HY-B0693S
产品使用指南 技术支持

Ranitidine-d6 是 Ranitidine (HY-B0693) 的氘代物。Ranitidine 是一种强效、选择性、具有口服活性的组胺 H2 受体 (histamine H2-receptor) 拮抗剂，可抑制胃液分泌。Ranitidine 可拮抗 Histamine (HY-B1204) 诱导的豚鼠离体大鼠心房扩张和组胺诱导的大鼠离体子宫角松弛，pA2 值分别为 7.2 和 6.95。Ranitidine 可抑制小鼠乳腺肿瘤的发展和扩散。

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Ranitidine-d<sub>6</sub>

Ranitidine-d6 Chemical Structure

CAS No. : 1185514-83-3

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Ranitidine-d6 的其他形式现货产品:

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Ranitidine-d6 相关抗体

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

  • 生物活性

  • 纯度 & 产品资料

生物活性

Ranitidine-d6 is the deuterium labeled Ranitidine (HY-B0693). Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine antagonizes Histamine (HY-B1204)-induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine inhibits breast tumor development and spread in mice[1][2].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ranitidine-d6 相关抗体:
分子量

320.44

Formula

C13H16D6N4O3S
CAS 号
非标记 CAS
中文名称

雷尼替丁-d6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Ranitidine-d6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ranitidine-d61185514-83-3雷尼替丁-d6Histamine ReceptorIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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