Animal-Free Galectin-8/LGALS8 蛋白, Human (His)

Galectin-8/LGALS8 Protein, a vital enzyme in glycosylation, serves as a beta-1,3-N-acetylglucosaminyltransferase, synthesizing poly-N-acetyllactosamine. Crucial for modifying glycoproteins and glycolipids, Galectin-8/LGALS8 catalyzes N-acetylglucosamine transfer onto acceptor molecules, exhibiting specific activity for type 2 oligosaccharides. Its role in poly-N-acetyllactosamine synthesis emphasizes its significance in modulating cellular interactions, impacting various processes like cell adhesion, signaling, and recognition events through glycan structure alterations. Animal-Free Galectin-8/LGALS8 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-8/LGALS8 protein, expressed by E. coli, with N-His labeled tag. The total length of Animal-Free Galectin-8/LGALS8 Protein, Human (His) is 316 a.a., with molecular weight of ~36.6 kDa.

B3GNT4 是糖基化过程中的关键酶，充当 β-1,3-N-乙酰氨基葡萄糖转移酶，负责合成聚-N-乙酰乳糖胺。该酶通过催化 N-乙酰氨基葡萄糖残基转移到受体分子上，在糖蛋白和糖脂的修饰中发挥着至关重要的作用。值得注意的是，B3GNT4 对 2 型寡糖表现出特异性活性，有助于聚糖结构的多样化和复杂性。B3GNT4 合成聚-N-乙酰基乳糖胺强调了其在调节细胞相互作用中的重要性，因为聚糖结构的改变可以影响各种生物过程，包括细胞粘附、信号传导和识别事件。

Measured by its ability to agglutinate human red blood cells. The ED₅₀ for this effect is <8 μg/mL.

Human

E. coli

N-His

O00214 (M2-W317)

3964  [NCBI]

MLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGEEERNITSFPFSPGMYFEMIIYCDVREFKVAVNGVHSLEYKHRFKELSSIDTLEINGDIHLLEVRSW

Approximately 36.6 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.