1. 重组蛋白
  2. Cytokines and Growth Factors
  3. EGF Superfamily
  4. EGFL7/VE-Statin 蛋白, Human (sf9, His)

EGFL7/VE-Statin 蛋白, Human (sf9, His)

目录号: HY-P75730
产品使用指南

EGFL7/VE-他汀是血管动力学的重要协调者,影响体内血管生成并抑制PDGF-BB诱导的平滑肌细胞迁移,从而影响血管重塑。它在促进内皮细胞粘附方面发挥关键作用,并有助于血管生成,强调其对血管发育的调节影响。EGFL7/VE-Statin 蛋白, Human (sf9, His) 是重组的 EGFL7/VE-他汀蛋白,由 Sf9 insect cells 表达,带有 N-His 标签。EGFL7/VE-Statin 蛋白, Human (sf9, His) 全长 250 个氨基酸,分子量约为 ~31 kDa。

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描述

EGFL7/VE-statin is an important coordinator of vascular dynamics, affecting angiogenesis in vivo and inhibiting PDGF-BB-induced smooth muscle cell migration, thereby affecting vascular remodeling. It plays a key role in promoting endothelial cell adhesion and contributes to angiogenesis, emphasizing its regulatory influence on vascular development. EGFL7/VE-Statin Protein, Human (sf9, His) is the recombinant human-derived EGFL7/VE-Statin protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of EGFL7/VE-Statin Protein, Human (sf9, His) is 250 a.a., with molecular weight of ~31 kDa.

研究背景

EGFL7,也称为 VE-他汀,是血管动力学的重要协调者,在体内血管生成中发挥着重要作用。这种多功能蛋白对血小板衍生生长因子 (PDGF)-BB 诱导的平滑肌细胞迁移具有抑制作用,从而影响血管重塑。此外,EGFL7 在促进内皮细胞粘附到细胞外基质方面发挥着关键作用,并有助于血管生成,强调其对血管发育的调节影响。通过以 RGD 依赖性方式与 ITGAV/ITGB3 相互作用,EGFL7 增强内皮细胞运动性,进一步强调其参与控制血管功能和稳态的复杂过程。

种属

Human

表达系统

Sf9 insect cells

标签

N-His

蛋白编号

Q9UHF1 (Y24-S273)

基因 ID
蛋白结构
N-term
His
EGFL7 (Y24-S273)
Accession # Q9UHF1
C-term
同用名
Epidermal growth factor-like protein 7; NOTCH4-like protein; VE-statin; MEGF7
分子量

Approximately 31 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

EGFL7/VE-Statin Protein, Human (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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EGFL7/VE-Statin Protein, Human (sf9, His)
目录号:
HY-P75730
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