GM-CSF R alpha 蛋白, Cynomolgus (298.a.a, HEK293, His)

GM-CSF R alpha Protein, a crucial type I cytokine receptor in the Type 5 subfamily, plays an essential role in mediating cellular responses to various cytokines. Sharing conserved features with related receptors, it transduces signals from specific type I cytokines, emphasizing its unique contributions to hematopoiesis and immune regulation within the broader context of cell signaling. Understanding GM-CSF R alpha's role holds promise for therapeutic interventions in hematopoietic disorders and immune dysregulation. GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is the recombinant cynomolgus-derived GM-CSF R alpha protein, expressed by HEK293, with C-His labeled tag. The total length of GM-CSF R alpha Protein, Cynomolgus (298.a.a, HEK293, His) is 298 a.a., with molecular weight of 60-70 kDa.

GM-CSF R α 蛋白是 I 型细胞因子受体家族的重要成员，特别归类于 5 型亚家族，突出了其在介导细胞对各种细胞因子的反应中的重要作用。作为该受体家族的一部分，GM-CSF R α 可能与相关受体具有保守的结构和功能特征，强调其参与转导来自特定 I 型细胞因子的信号。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称，从而深入了解其对造血和免疫调节的独特贡献。GM-CSF R α 的研究有助于我们了解其在生理过程中的作用，为造血障碍和免疫失调相关疾病的治疗干预提供了潜在的应用。对 GM-CSF R α 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

Cynomolgus

HEK293

C-His

A0A2K5UC70 (L20-S317)

/

60-70 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.