1. 重组蛋白
  2. Receptor Proteins
  3. IGFLR1 蛋白, Human (HEK293, Fc)

IGFLR1 蛋白, Human (HEK293, Fc)

目录号: HY-P77396
产品使用指南

IGFLR1 蛋白是一种可能的细胞膜受体,对 IGF 样家族蛋白 IGFL1 和 IGFL3 表现出特异性亲和力,与其他蛋白相比具有更高的结合亲和力。这种选择性相互作用表明 IGFLR1 在介导细胞对这些配体的反应中发挥着关键作用,强调了它在复杂的细胞信号通路网络中的重要性。IGFLR1 蛋白, Human (HEK293, Fc) 是重组的 IGFLR1 蛋白,由 HEK293 表达,带有 C-hFc 标签。IGFLR1 蛋白, Human (HEK293, Fc) 全长 159 个氨基酸,分子量分别约为 ~58.9 & 47.6 kDa。

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描述

IGFLR1 protein, a probable cell membrane receptor, exhibits specific affinity for IGF-like family proteins IGFL1 and IGFL3, with higher binding affinity compared to others. This selective interaction profile suggests a key role for IGFLR1 in mediating cellular responses to these ligands, emphasizing its significance in the intricate network of cellular signaling pathways. IGFLR1 Protein, Human (HEK293, Fc) is the recombinant human-derived IGFLR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFLR1 Protein, Human (HEK293, Fc) is 159 a.a., with molecular weight of ~58.9 & 47.6 kDa, respectively.

研究背景

IGFLR1 蛋白可能是 IGF 样家族蛋白的细胞膜受体,表现出对 IGFL1 和 IGFL3 的特异性亲和力,与其他家族成员相比具有更高的结合亲和力。这表明 IGFLR1 和这些配体之间存在选择性相互作用。此外,IGFLR1 还可能表现出结合 IGFL2 的能力,进一步扩展其潜在的配体库。独特的结合偏好强调了受体在介导细胞对 IGF 样家族蛋白反应中的作用,强调了它在复杂的细胞信号通路网络中的重要性。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q9H665 (M1-P159)

基因 ID
蛋白结构
N-term
IGFLR1 (M1-P159)
Accession # Q9H665
hFc
C-term
同用名
IGF-like family receptor 1; Transmembrane protein 149; TMEM149; U2AF1L4
分子量

Approximately 58.9&47.6 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IGFLR1 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IGFLR1 Protein, Human (HEK293, Fc)
目录号:
HY-P77396
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