L1CAM 蛋白, Human (HEK293, His)

The L1CAM protein is a neural cell adhesion molecule that plays a critical role in cell adhesion dynamics and initiation of tyrosine kinase receptor transmembrane signaling. Its importance spans brain development, affecting processes such as neuronal migration, axonal growth, fasciculations, and synaptogenesis. L1CAM Protein, Human (HEK293, His) is the recombinant human-derived L1CAM protein, expressed by HEK293 , with C-His labeled tag. The total length of L1CAM Protein, Human (HEK293, His) is 1101 a.a., with molecular weight of 160-200 kDa.

L1CAM 是一种神经细胞粘附分子，复杂地参与细胞粘附动力学的调节和酪氨酸激酶受体跨膜信号的启动。它的重要性跨越大脑发育的各个阶段，在神经元迁移、轴突生长、束颤和突触发生等过程中发挥着至关重要的作用。在成熟的大脑中，L1CAM 在调节神经元结构和功能的动态方面继续发挥着关键作用，特别是有助于突触可塑性。这种多面蛋白与 SHTN1 相互作用，这种相互作用主要发生在轴突生长锥中，并与 BSG 亚型 2 结合，强调了它参与多种细胞功能。

Human

HEK293

C-His

P32004 (I20-E1120)

3897  [NCBI]

160-200 kDa

Greater than 90% as determined by reducing SDS-PAGE

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.