Neuropoietin 蛋白, Mouse

Neurogenin, a protein associated with elevated platelet counts and splenomegaly, is involved in neuronal precursor development and maturation. By binding to the CNTF receptor complex (including CNTF alpha chain, LIFR and IL6ST), neurogenin may affect signaling pathways related to cell differentiation. Neuropoietin Protein, Mouse is the recombinant mouse-derived Neuropoietin protein, expressed by E. coli , with tag free.

神经生成素是一种与血小板计数增加和脾肿大相关的蛋白质，可能在神经元前体发育和成熟中发挥至关重要的作用。它通过与三方 CNTF 受体复合物结合发挥作用，该复合物包含 CNTF α 链、LIFR 和 IL6ST。体外观察到的这种相互作用表明神经生成素参与与细胞分化和成熟过程相关的信号通路。该蛋白质在血小板调节和神经发育中的双重作用强调了其在不同生理环境中的多功能性和潜在意义。

Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is 50-200 ng/mL.

Mouse

E. coli

Tag Free

P83714 (A23-A204)

244218  [NCBI]

Full Length of Mature Protein

Approximately 20 kDa, based on SDS-PAGE under reducing conditions.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.