2. 重组蛋白
  3. Cytokines and Growth Factors CD Antigens Receptor Proteins Enzymes & Regulators
  4. PDGFs & PDGFRs Platelet CD Proteins Endothelial cell CD Proteins Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. CD140b/PDGF-R-beta PDGFR
  6. PDGF-R-beta
  7. PDGF R beta 蛋白, Human (HEK293, Fc)

PDGF R beta 蛋白, Human (HEK293, Fc)

目录号: HY-P77124
产品使用指南

TRF1蛋白是一种端粒结合蛋白，在端粒维持和染色体稳定性中发挥着至关重要的作用。它参与调节端粒长度和防止 DNA 损伤。PDGF R beta 蛋白, Human (HEK293, Fc) 是重组的 PDGF R β 蛋白，由 HEK293 表达，带有 C-hFc 标签。PDGF R beta 蛋白, Human (HEK293, Fc) 全长 498 个氨基酸，分子量约为 ~82.8 KDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

TRF1 protein is a telomere-binding protein that plays a crucial role in telomere maintenance and chromosome stability. It is involved in regulating telomere length and preventing DNA damage. PDGF R beta Protein, Human (HEK293, Fc) is the recombinant human-derived PDGF R beta protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PDGF R beta Protein, Human (HEK293, Fc) is 498 a.a., with molecular weight of ~82.8 KDa.
研究背景

PDGF R beta 蛋白编码细胞表面酪氨酸激酶受体，该受体与血小板衍生生长因子家族的成员相互作用，血小板衍生生长因子家族是间充质来源细胞的已知有丝分裂原。与受体单体结合的生长因子的特性决定了功能性受体是否形成同二聚体（与PDGFB或PDGFD）或异二聚体（与PDGFA和PDGFB）。该基因对于正常心血管系统发育和肌动蛋白细胞骨架的重排至关重要，该基因位于 5 号染色体上，两侧是粒细胞-巨噬细胞集落刺激因子和巨噬细胞集落刺激因子受体基因，所有三个基因都可能与 5-q 相关。综合症。5 号和 12 号染色体之间的易位导致该基因与 ETV6 基因融合，导致伴有嗜酸性粒细胞增多的慢性骨髓增殖性疾病。PDGF R beta 基因广泛表达，在胆囊 (RPKM 79.5)、胎盘 (RPKM 61.0) 和 21 个其他组织中表现出升高的水平，表明它参与多个器官的不同生理环境。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

NP_002600.1 (L33-F530)
基因 ID
蛋白结构
N-term
PDGF R beta (L33-F530)
Accession # NP_002600.1
hFc
C-term
同用名
Platelet-derived growth factor receptor beta; PDGF-R-beta; PDGFR-1; CD140b; PDGFRB
分子量

Approximately 82.8 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PDGF R beta Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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