1. 重组蛋白
  2. Cytokines and Growth Factors
  3. TPO/Thrombopoietin 蛋白, Mouse (CHO)

TPO/Thrombopoietin 蛋白, Mouse (CHO)

目录号: HY-P7088
COA 产品使用指南

TPO 蛋白, Mouse (CHO)是一种造血因子,能够控制血小板生长。

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规格 价格 是否有货 数量
10 μg ¥1900 In-stock
50 μg ¥5900 In-stock
100 μg ¥8600 询价
250 μg   询价  

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描述

TPO Protein, Mouse (CHO) is a hematopoietic factor that controls platelet production.

研究背景

Recombinant thrombopoietin reduces radiation- and chemotherapy-induced thrombocytopenia, enhances platelet recovery after bone marrow transplantation and increases the number of megakaryocyte precursor cells in stem cell harvests. Injection of thrombopoietin into animals stimulates the number, size and ploidy of bone marrow megakaryocytes and increases the platelet count up to ten-fold[1]. Superphysiological amounts of Thrombopoietin/TPO (>100 ng/mL) are able to directly activate platelet aggregation in vitro. Thrombopoietin/TPO also has significant effects on platelet adhesion under flow. Low Thrombopoietin/TPO concentrations (001-1 ng/mL) accelerate firm platelet adhesion to von Willebrand factor and prevent de-attachment at higher flow rates[2].

生物活性

The ED50 is <2 ng /mL as measured by MO7e cells.

种属

Mouse

表达系统

CHO

标签

Tag Free

蛋白编号

P40226 (S22-T356)

基因 ID

21832  [NCBI]

中文名
重组小鼠促血小板生成素 (CHO 细胞表达)
同用名
rMuTPO; TPO
氨基酸序列

SPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHG

分子量

30-80 kDa

性状

Lyophilized powder.

组分

Lyophilized after extensive dialysis against PBS.

内毒素含量

<0.2 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O or PBS.

保存条件 & 期限

Stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
参考文献

TPO/Thrombopoietin Protein, Mouse (CHO) 相关分类

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific active calculator equation

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Active (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TPO/Thrombopoietin Protein, Mouse (CHO)
目录号:
HY-P7088
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