1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 老药新用化合物库系列
  5. 临床化合物库
临床化合物库 - Clinical Compound Library

Cat. No.: HY-L026

新药研发是一个耗时且成本高昂的开发过程。与新药研发相比,药物重定位 (也称为老药新用) 具有很多优势,比如开发风险低,投入成本少等。临床期药物具有明确的活性及作用机制,安全性较高,非常适合老药新用的研究。

MCE 收录了 2219 种临床化合物,涉及抗肿瘤、抗感染、抗炎,神经疾病等多个研究领域。这些化合物都具有详细的临床阶段、研究领域及靶点等生物信息。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 临床化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,2158 个产品以 10 mM 浓度提供,50 个产品以 2 mM 浓度提供,11 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2219 clinical compounds for high throughput screening (HTS) and high content screening (HCS).

•   Research areas include anticancer, anti-infection, anti inflammation, nervous disease, and more.

•   A useful tool for drug repurposing.

•   Currently in clinical stage, some are withdrawn or terminated.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 2219 clinical compounds supplied as pre-dissolved Solutions or Solid
Solution: 2158 compounds supplied in 10 mM solution, 50 compounds supplied in 2 mM solution, 11 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

VEGFR (53)

EGFR (50)

PI3K (50)

CDK (36)

HIV (35)

JAK (33)

FGFR (30)

FLT3 (30)

iGluR (29)

PPAR (29)

mTOR (27)

Akt (26)

HDAC (25)

PDGFR (24)

Btk (20)

HCV (20)

HSP (20)

CXCR (19)

CCR (18)

c-Kit (17)

mGluR (16)

MMP (16)

PARP (16)

c-Fms (15)

HBV (15)

MEK (15)

mAChR (14)

Src (13)

ERK (12)

Raf (12)

nAChR (11)

Syk (11)

COX (10)

FXR (10)

AMPK (9)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Clinical Compound Library
    目录号:
    HY-L026
    需求量: