2. Protein Tyrosine Kinase/RTK
  3. SHP2
  4. SHP2-IN-28

SHP2-IN-28 (Compound 7188-0011) 是 Src 同源 2- 含蛋白酪氨酸磷酸酶 2 (SHP2) 的抑制剂 (IC50=54.31 μM)。通过与 SHP2 的变构位点结合发挥抑制作用，具有较高的选择性。

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SHP2-IN-28 Chemical Structure

SHP2-IN-28 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

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SHP2-IN-28 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SHP2-IN-28 (Compound 7188-0011) is an inhibitor of SHP2 (IC50=54.31 μM). SHP2-IN-28 exerts its inhibitory effect by binding to the variable site of SHP2 with high selectivity[1].

分子量

261.32

Formula

C14H19N3O2
非同位 CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SHP2-IN-28 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SHP2-IN-28SHP2Src homology phosphatase 2PTPN11Allosteric inhibitorProtein tyrosine phosphatasecancerInhibitorinhibitorinhibit

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产品名称：
SHP2-IN-28
目录号：
HY-162476
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