1. Immunology/Inflammation
  2. CD3
  3. Solitomab

Solitomab  (Synonyms: AMG 110; MT110)

目录号: HY-P99592 纯度: 98.15%
COA

Solitomab (AMG 110) 是一种双特异性的抗 CD3 和抗上皮细胞粘附分子 (EpCAM) 抗体。Solitomab 可用于原发性子宫癌和卵巢癌肉瘤的研究。

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Solitomab Chemical Structure

Solitomab Chemical Structure

CAS No. : 1005198-65-1

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规格 价格 是否有货 数量
1 mg ¥8000
In-stock
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Solitomab (AMG 110) is a bispecific anti-CD3 and anti-epithelial-cell-adhesion-molecule (EpCAM) antibody. Solitomab can be used for the research of primary uterine and ovarian carcinosarcoma cancer[1][2].

体外研究
(In Vitro)

Solitomab (1 μg/mL;4 小时) 对 EpCAM 阳性细胞株显示细胞毒性,并增加 EpCAM 阳性肉瘤 (CS) 细胞对 T 细胞细胞毒性的敏感性[1]
Solitomab (7 天) 增加 CD8+CD4+ T 细胞表面 CD25 和 HLA-DR 蛋白 (T 细胞激活标记物) 的表达水平[1]
Solitomab (0-2.5 μg/mL;4 小时) 对卵巢癌细胞有细胞毒作用,1 μg/mL 剂量对肿瘤杀伤效果最好[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: 98.15%

参考文献

Solitomab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Solitomab
目录号:
HY-P99592
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