1. Anti-infection
  2. Bacterial Parasite Antibiotic
  3. Sulfaclozine sodium

Sulfaclozine sodium  (Synonyms: Sulfachloropyrazine sodium)

目录号: HY-19285A 纯度: 99.20%
COA 产品使用指南

Sulfaclozine sodium (Sulfachloropyrazine sodium) 是一种有效的磺酰胺衍生物,具有抗菌和抗球虫作用。Sulfaclozine sodium 通常用于各种家禽疾病(尤其是结肠杆菌病,禽霍乱和球虫病)的相关研究。

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Sulfaclozine sodium Chemical Structure

Sulfaclozine sodium Chemical Structure

CAS No. : 23307-72-4

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规格 价格 是否有货 数量
10 mM * 1 mL in Water ¥550
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100 mg ¥500
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500 mg   询价  

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Customer Review

Other Forms of Sulfaclozine sodium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulfaclozine sodium (Sulfachloropyrazine sodium) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis)[1].

IC50 & Target

Coccidia

 

体外研究
(In Vitro)

The elimination of Sulfaclozine in the three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8. Sulfaclozine is weakly adsorbed on the surface of TiO2 at pH 7 (< 5%) but efficiently eliminated with the following three systems: UV/TiO2, UV/K2S2O8, and UV/TiO2/K2S2O8 in ultra pure water. Moreover, 12 of Sulfaclozine by-products are identified and reaction pathways show that, in addition of OH and SO4•− radicals, the conduction-band electrons are responsible for the formation of some main by-products either directly or by the formation of superoxide radicals[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Sulfaclozine (60 mg/kg; intravenous injection or oral administration; male broiler chickens) can be used primarily for the treatment of parasitic and microbial infections of the digestive tract rather than for the treatment of systemic infections[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 14 male broiler chickens (30-day-old)[1]
Dosage: 60 mg/kg
Administration: Intravenous injection or oral administration (Pharmacokinetic Analysis)
Result: Serum drug concentrations at 0.083, 0.50, 2, 6, 24 and 72h were determined to be 99.62, 83.50, 72.68, 58.43, 38.66 and 13.14 μg/mL, respectively, by intravenous injection. By oral administration were determined as 4.33, 7.95, 16.46, 22.88, 16.03 and 5.74 μg/mL, respectively.
分子量

306.70

Formula

C10H8ClN4NaO2S

CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O 中的溶解度 : 50 mg/mL (163.03 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.2605 mL 16.3026 mL 32.6051 mL
5 mM 0.6521 mL 3.2605 mL 6.5210 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

Sulfaclozine sodium 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.2605 mL 16.3026 mL 32.6052 mL 81.5129 mL
5 mM 0.6521 mL 3.2605 mL 6.5210 mL 16.3026 mL
10 mM 0.3261 mL 1.6303 mL 3.2605 mL 8.1513 mL
15 mM 0.2174 mL 1.0868 mL 2.1737 mL 5.4342 mL
20 mM 0.1630 mL 0.8151 mL 1.6303 mL 4.0756 mL
25 mM 0.1304 mL 0.6521 mL 1.3042 mL 3.2605 mL
30 mM 0.1087 mL 0.5434 mL 1.0868 mL 2.7171 mL
40 mM 0.0815 mL 0.4076 mL 0.8151 mL 2.0378 mL
50 mM 0.0652 mL 0.3261 mL 0.6521 mL 1.6303 mL
60 mM 0.0543 mL 0.2717 mL 0.5434 mL 1.3585 mL
80 mM 0.0408 mL 0.2038 mL 0.4076 mL 1.0189 mL
100 mM 0.0326 mL 0.1630 mL 0.3261 mL 0.8151 mL

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Sulfaclozine sodium
目录号:
HY-19285A
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