1. PI3K/Akt/mTOR Apoptosis
  2. PI3K Apoptosis
  3. WNY1613

WNY1613 是一种有效的选择性 PI3Kδ 抑制剂,具有含有哌嗪酮的嘌呤支架。WNY1613 诱导癌细胞凋亡 (apoptosis) 并抑制 NHL 细胞系中 PI3K 下游成分的磷酸化。WNY1613 在体外和体内均表现出抗 NHL 活性。

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WNY1613 Chemical Structure

WNY1613 Chemical Structure

CAS No. : 2650546-39-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

WNY1613 is a potent and selective PI3Kδ inhibitor with piperazinone-containing purine scaffold. WNY1613 induces cancer cell apoptosis and inhibits the phosphorylation of PI3K downstream components in NHL cell lines. WNY1613 exhibits anti-NHL activity in vitro and in vivo[1].

分子量

557.65

Formula

C29H35N9O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

WNY1613 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
WNY1613
目录号:
HY-147792
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