2. Cell Cycle/DNA Damage Epigenetics
  3. PARP
  4. XAV-939

XAV-939 (GMP) 是 GMP 级别的 XAV-939 (HY-15147)。GMP 级别的小分子可用做细胞疗法中的辅助试剂。XAV-939 是一种 tankyrase 抑制剂。

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XAV-939 Chemical Structure

XAV-939 Chemical Structure

CAS No. : 284028-89-3

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规格 价格 是否有货 数量
10 mg ￥8640
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Customer Review

Other Forms of XAV-939:

XAV-939 相关抗体

Top Publications Citing Use of Products

查看 PARP 亚型特异性产品:

查看所有亚型
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

XAV-939 (GMP) is XAV-939 (HY-15347) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XAV-939 is a tankyrase inhibitor[1].

体外研究
(In Vitro)

XAV-939 (GMP) (5 μM; 2 μM for 3 days; 1 μM) induces human pluripotent stem cells (hPSCs) to post-mitotic cortical neurons differentiation[1].
XAV939 (GMP) promotes anterior CNS identity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

XAV-939 相关抗体:

RT-PCR[1]

Cell Line: Human pluripotent stem cells (hPSCs)
Concentration: 5 μM, 2 μM, 1 μM
Incubation Time: 3 days
Result: Showed downregulation of the pluripotency marker OCT4 and induction of neural and neuronal markers PAX6, FOXG1 and DCX, as well as markers of early born cortical neurons, including TBR1 (preplate, subplate and layer VI) and REELIN, in LSB+X/P/S/D conditions.
分子量

312.31

Formula

C14H11F3N2OS
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

XAV-939 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XAV-939 (GMP)284028-89-3PARPpoly ADP ribose polymerasemidbrain dopamine (mDA)neurontankyrasehuman pluripotent stem cells (hPSCs)Inhibitorinhibitorinhibit

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产品名称：
XAV-939
目录号：
HY-15147G
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