2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. β-Endorphin (1-27) (human)

β-Endorphin (1-27) (human) 是一种 opioid 拮抗剂，结合 μ-、δ- 和 κ-阿片受体，其 Kis 分别为 5.31、6.17 和 39.82 nM。β-Endorphin (1-27) (human) 抑制 β-Endorphin (HY-P1502) 诱导和 etorphine 诱导的痛觉缺失。

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β-Endorphin (1-27) (human) Chemical Structure

β-Endorphin (1-27) (human) Chemical Structure

CAS No. : 76622-84-9

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β-Endorphin (1-27) (human) 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-Endorphin (1-27) (human) is an opioid antagonist that binds μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. β-Endorphin (1-27) (human) inhibits β-Endorphin (HY-P1502)-induced and etorphine-induced analgesia[1][2].

IC50 & Target

Ki: 5.31 nM (μ-opioid receptor), 6.17 nM (δ-opioid receptor), 39.82 nM (κ-opioid receptor)[1]
分子量

3022.47

Formula

C139H217N33O40S
CAS 号
Sequence

Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr
Sequence Shortening

YGGFMTSEKSQTPLVTLFKNAIIKNAY
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

β-Endorphin (1-27) (human) 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Endorphin (1-27) (human)76622-84-9Opioid Receptoranalgesiaβ-EndorphinetorphineInhibitorinhibitorinhibit

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