2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Opioid Receptor NO Synthase
  4. β-Funaltrexamine hydrochloride

β-Funaltrexamine hydrochloride  (Synonyms: β-富纳曲胺盐酸盐; β-FNA hydrochloride)

目录号: HY-101318 纯度: 98.0%
COA 产品使用指南 技术支持

β-Funaltrexamine (β-FNA) hydrochloride 是一种选择性 μ 阿片受体拮抗剂。β-Funaltrexamine hydrochloride 还能抑制细胞因子诱导的 iNOS 激活。β-Funaltrexamine hydrochloride 可抑制神经炎症并改善神经元退化。β-Funaltrexamine hydrochloride 具有抗炎和神经保护作用，可用于神经退行性疾病 (例如中风) 的研究。

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β-Funaltrexamine hydrochloride Chemical Structure

β-Funaltrexamine hydrochloride Chemical Structure

CAS No. : 72786-10-8

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规格 价格 是否有货 数量
1 mg ￥2250
In-stock
5 mg ￥5600
In-stock
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β-Funaltrexamine hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Opioid Receptor 亚型特异性产品:

查看所有亚型
μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-Funaltrexamine (β-FNA) hydrochloride is a selective μ opioid receptor antagonist. β-Funaltrexamine hydrochloride also inhibits cytokine-induced iNOS activation. β-Funaltrexamine hydrochloride inhibits neuroinflammation and ameliorated neuronal degeneration. β-Funaltrexamine hydrochloride has anti-inflammatory and neuroprotective effects and can be used for research of neurodegenerative diseases (eg: stroke)[1][2]

IC50 & Target[1][2]

μ Opioid Receptor/MOR

 

iNOS

 

分子量

490.98

Formula

C25H31ClN2O6
CAS 号
性状

固体

颜色

White to off-white

中文名称

β-富纳曲胺盐酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

β-Funaltrexamine hydrochloride 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Funaltrexamine72786-10-8β-FNAβ-富纳曲胺盐酸盐Opioid ReceptorNO SynthaseNitric oxide synthasesNOSanti-inflammatoryneuroprotectivestrokeInhibitorinhibitorinhibit

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