1. Stem Cell/Wnt Vitamin D Related/Nuclear Receptor
  2. β-catenin Wnt Androgen Receptor
  3. β-catenin inhibitory peptoid

β-catenin inhibitory peptoid (compound 13) 可抑制 β-catenin 与 TCF 的相互作用,IC50 为 5.44 µM。β-catenin inhibitory peptoid 可抑制前列腺癌细胞系中的 Wnt信号传导 (IC50 为 0.105 µM) 和雄激素受体 (AR) 信号传导 (IC50 为 1.02 µM)。β-catenin inhibitory peptoid 可显著抑制前列腺癌细胞系的细胞增殖。

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β-catenin inhibitory peptoid Chemical Structure

β-catenin inhibitory peptoid Chemical Structure

CAS No. : 2579070-02-1

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生物活性

β-catenin inhibitory peptoid (compound 13) inhibits the β-catenin:TCF interaction with an IC50 of 5.44 µM. β-catenin inhibitory peptoid inhibits both Wnt (IC50 of 0.105 µM) and androgen receptor (AR)-signaling (IC50 of 1.02 µM) in prostate cancer cell lines. β-catenin inhibitory peptoid markedly diminishes cell proliferation of prostate cancer cell lines[1].

分子量

1057.24

Formula

C59H72N6O12

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
β-catenin inhibitory peptoid
目录号:
HY-P11007
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