2. Immunology/Inflammation
  3. CD1 IFNAR Interleukin Related
  4. Anti-CD1a Antibody (OKT-6)

Anti-CD1a Antibody (OKT-6) 

目录号: HY-P990869
技术支持

Anti-CD1a Antibody (OKT-6) 是一种抗人 CD1a IgG1 单克隆抗体。Anti-CD1a Antibody (OKT-6) 通过阻断 CD1a 功能来阻断 T 细胞活化。Anti-CD1a Antibody (OKT-6) 可以减少 IFN-γ 的产生。Anti-CD1a Antibody (OKT-6) 可用于癌症和炎症的研究如白血病。Anti-CD1a Antibody (OKT-6) 的同型对照为 Mouse IgG1 kappa, Isotype Control (HY-P99977)。

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Anti-CD1a Antibody (OKT-6)

Anti-CD1a Antibody (OKT-6) Chemical Structure

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5 mg   询价  
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Anti-CD1a Antibody (OKT-6) 相关抗体

Top Publications Citing Use of Products

查看 Interleukin Related 亚型特异性产品:

查看所有亚型
IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-CD1a Antibody (OKT-6) is an anti-human CD1a IgG1 monoclonal antibody. Anti-CD1a Antibody (OKT-6) blocks T cell activation by blocking CD1a function. Anti-CD1a Antibody (OKT-6) can reduce the production of IFN-γ. Anti-CD1a Antibody (OKT-6) can be used for researches on cancer and inflammation such as leukemia. The recommend isotype control of Anti-CD1a Antibody (OKT-6): Mouse IgG1 kappa, Isotype Control (HY-P99977)[1][2].

同型

Mouse IgG1 kappa
反应种属

Human
IC50 & Target[1][2]

CD1a

 

IL-13

 

IL-22

 

体外研究
(In Vitro)

Anti-CD1a Antibody (OKT-6) (10 μg/mL) 显著抑制蜂毒或磷脂酶 A2 (PLA2) 在 K562-CD1a 细胞中诱导的 IFN-γ 产生[1]。
Anti-CD1a Antibody (OKT-6) (10 μg/mL) 可以阻断 PLA2 或蜂毒诱导的 T 细胞活化[1]。
Anti-CD1a Antibody (OKT-6) (10 μg/mL，1 小时) 显著抑制由屋尘螨 (HDM)、PLA2G4A 或金黄色葡萄球菌诱导的第 2 组先天淋巴细胞 (ILC2) 中 IFN-γ 和 IL-22 的产生[2]。
Anti-CD1a Antibody (OKT-6) (10 μg/mL) 抑制 T 细胞产生 IL-13 和金黄色葡萄球菌诱导的 T 细胞活化[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-CD1a Antibody (OKT-6) 相关抗体:

ELISA Assay[2]

Cell Line: Preprocess ILC2 for 1 h, subsequently co-cultured with T cells for 24 h
Concentration: 10 μg/mL
Incubation Time: 1 h
Result: Significantly reduced the levels of IFN-γ and IL-22.
基因 ID

909  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-CD1a Antibody (OKT-6) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-CD1a Antibody (OKT-6)CD1IFNARInterleukin RelatedInterferon-α/β receptorInterferon-alpha/beta receptor ILCD1aT cellIFN-γIL-22IL-13K562Inhibitorinhibitorinhibit

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目录号：
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