2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Mouse CD31/PECAM-1 Antibody (390)

Anti-Mouse CD31/PECAM-1 Antibody (390) 

目录号: HY-P990277 纯度: ≥95.0%
COA 技术支持

Anti-Mouse CD31/PECAM-1 Antibody (390) 是一种源自大鼠的 IgG2a κ 型抗体抑制剂，靶向小鼠 CD31/PECAM-1。Anti-Mouse CD31/PECAM-1 Antibody (390) 与小鼠 CD31 (也称为血小板内皮细胞黏附分子-1，PECAM-1) 发生反应。Anti-Mouse CD31/PECAM-1 Antibody (390) 抑制血管生成。Anti-Mouse CD31/PECAM-1 Antibody (390) 可用于癌症研究，如 A549 肿瘤。

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Anti-Mouse CD31/PECAM-1 Antibody (390)

Anti-Mouse CD31/PECAM-1 Antibody (390) Chemical Structure

1.  客户无需承担相应的运输费用。

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规格 价格 是否有货 数量
1 mg ￥1800
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Anti-Mouse CD31/PECAM-1 Antibody (390) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD31/PECAM-1 Antibody (390) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD31/PECAM-1. Anti-Mouse CD31/PECAM-1 Antibody (390) reacts with mouse CD31, also known as PECAM-1 (platelet endothelial cell adhesion molecule). Anti-Mouse CD31/PECAM-1 Antibody (390) inhibits angiogenesis. Anti-Mouse CD31/PECAM-1 Antibody (390) can be used for the research of cancer, such as A549 tumor[1][2].

同型

Rat IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

CD31/PECAM-1
体外研究
(In Vitro)

Anti-Mouse CD31/PECAM-1 Antibody (390) (100 μg/mL, 15 mins) 可抑制 H5V 小鼠内皮细胞在基质胶上形成管[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-Mouse CD31/PECAM-1 Antibody (390) 相关抗体:
体内研究
(In Vivo)

Anti-Mouse CD31/PECAM-1 Antibody (390) (200 μg，腹腔注射，每周三次) 可抑制 A549/B16/AB12 肿瘤模型小鼠中的肿瘤生长[1]。
Anti-Mouse CD31/PECAM-1 Antibody (390) (50 μg，腹腔注射，连续 7 天每天给药) 可完全抑制 C57BL/6 小鼠的血管生成[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: A549/B16/AB12 tumor mice models[1]
Dosage: 200 μg
Administration: Intraperitoneally injection, three times a week
Result: Inhibited tumor growth.
Showed extensive necrosis with little detectable staining of vessels in AB12 tumor.
基因 ID

18613  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (268 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Anti-Mouse CD31/PECAM-1 Antibody (390) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD31/PECAM-1 Antibody (390)Transmembrane GlycoproteinCD31PECAM-1AngiogenesisA549B16AB12H5VInhibitorinhibitorinhibit

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