2. Immunology/Inflammation
  3. PD-1/PD-L1
  4. Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2)

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 

目录号: HY-P990171 纯度: 99.46%
COA 技术支持

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 是原始 10F.9G2 抗体 (HY-P99145) 的重组嵌合版本。其可变区序列与原始 10F.9G2 相同，但恒定区序列已从大鼠 IgG2b 转换为小鼠 IgG2a。Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 在 Fc 片段中含有 LALA-PG 突变，使其无法结合内源性 Fcγ 受体。Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 阻断 PD-1 信号传导。Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 可用于癌症研究。

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规格 价格 是否有货 数量
1 mg ￥900
In-stock
5 mg ￥3200
In-stock
10 mg ￥5450
In-stock
50 mg   询价  
100 mg   询价  

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Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) is a recombinant chimeric version of the original 10F.9G2 antibody (HY-P99145). The variable domain sequences are identical to the original 10F.9G2 but the constant region sequences have been switched from rat IgG2b to mouse IgG2a. Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) contains a LALA-PG mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) blocks PD-1 signaling. Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) can be used for the research of cancer.

同型

Mouse IgG2a kappa
推荐同型对照抗体
反应种属

Mouse
IC50 & Target

PD-L1/B7-H1 (LALA-PG)
基因 ID

60533  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized Mouse PDL1 Protein, His Tag can bind Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) . The EC50 for this effect is 31.78 ng/mL.
纯度 & 产品资料

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2)PD-1/PD-L1PD-1/Programmed death-ligand 1PD-L1B7-H1PD-1LALA-PGCancerInhibitorinhibitorinhibit

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Anti-Mouse PD-L1/B7-H1 (LALA-PG) Antibody (10F.9G2)
目录号：
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