1. Immunology/Inflammation
  2. Transmembrane Glycoprotein
  3. Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A)

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) 

目录号: HY-P990236
技术支持

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) 是一种抗小鼠/老鼠/猴子/人 ICOS/CD278 IgG 单克隆抗体。Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) 在改善 T 细胞功能和免疫激活方面的效果有限。Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) 可用于研究癌症和感染疾病,如胶质瘤和乙型肝炎病毒感染。

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Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A)

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) is an anti-mouse/rat/monkey/human ICOS/CD278 IgG monoclonal antibody. Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) has limited effectiveness in improving T cell function and immune activation. Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) can be used for researches on cancer and infection conditions such as gliomas and hepatitis B virus infection [1][2].

同型

Armenian hamster IgG

推荐同型对照抗体
反应种属

Human/Mouse/Rat/Monkey

IC50 & Target

ICOS/CD278

体外研究
(In Vitro)

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) (5 μg/mL,4 天) 未能显著增加携带胶质瘤小鼠脾细胞中 IFNγ 的产生[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A) (100 μg,腹腔注射,单次剂量,T 细胞移植后 24 小时) 未能显著增强慢性乙型肝炎病毒 (HBV) 感染模型小鼠中 T 细胞的抗病毒活性[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HBV transgenic mice (8-10 weeks)[2]
Dosage: 100 μg
Administration: Intraperitoneal injection (i.p.), single dose, 24 h after T cell transplantation
Result: Failed to significantly reduce HBV replication.
基因 ID

54167  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse/Rat/Monkey/Human ICOS/CD278 Antibody (C398.4A)
目录号:
HY-P990236
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