2. Cell Cycle/DNA Damage Epigenetics Immunology/Inflammation Apoptosis
  3. HDAC DNA/RNA Synthesis NO Synthase Apoptosis
  4. anti-TNBC agent-12

anti-TNBC agent-12 (Compound 23a) 是一种多靶点抗肿瘤剂，靶向 HDAC6 (IC50=30.3 nM)、DNA，并能促使一氧化氮 (NO) 释放。anti-TNBC agent-12 能诱导肿瘤细胞凋亡和 G2/M 期细胞周期停滞。anti-TNBC agent-12 有望用于三阴性乳腺癌 (TNBC) 的研究。

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anti-TNBC agent-12

anti-TNBC agent-12 Chemical Structure

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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anti-TNBC agent-12 相关抗体

Top Publications Citing Use of Products

查看 HDAC 亚型特异性产品:

查看所有亚型
HDAC HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HDAC10 HDAC11 HD1 HD2

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

anti-TNBC agent-12 (Compound 23a) is a multi-target antitumor agent targeting HDAC6 (IC50=30.3 nM), DNA, and inducing nitric oxide (NO) release. anti-TNBC agent-12 induces tumor cell apoptosis and G2/M phase cell cycle arrest. anti-TNBC agent-12 is promising for research of triple-negative breast cancer (TNBC)[1].

分子量

628.61

Formula

C30H24N6O8S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

anti-TNBC agent-12 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

anti-TNBC agent-12HDACDNA/RNA SynthesisNO SynthaseApoptosisHistone deacetylasesNitric oxide synthasesNOSHDAC6DNANOInhibitorinhibitorinhibit

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产品名称：
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目录号：
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