HDAC Inhibitors

HDAC

HDAC1

HDAC2

HDAC3

HDAC4

HDAC5

HDAC6

HDAC7

HDAC8

HDAC9

HDAC10

HDAC11

HD1

HD2

HDAC Degraders, Inhibitors, Activators & Modulators

Product Name	HDAC	HDAC1	HDAC2	HDAC3	HDAC4	HDAC5	HDAC6	HDAC7	HDAC8	HDAC9	HDAC10	HDAC11	HD1	HD2	Purity
Trichostatin A	HDAC, IC₅₀: 1.8 nM														99.91%
4-Phenylbutyric acid	HDAC														99.98%
Vorinostat		HDAC1, ID₅₀: 10 nM		HDAC3, ID₅₀: 20 nM											99.96%
Valproic acid	HDAC, IC₅₀: 0.5-2 mM	HDAC1, IC₅₀: 400 μM													99.19%
Sulforaphane	HDAC														99.75%
PT3		HDAC1, IC₅₀: 1.05 μM	HDAC2, IC₅₀: 2.08 μM						HDAC8, IC₅₀: 15 μM						99.94%
TO-1187 TFA							HDAC6, DC₅₀: 5.81 nM								98.41%
Entinostat		HDAC1, IC₅₀: 243 nM	HDAC2, IC₅₀: 453 nM	HDAC3, IC₅₀: 248 nM											99.82%
Panobinostat	HDAC														99.37%
Romidepsin		HDAC1, IC₅₀: 36 nM	HDAC2, IC₅₀: 47 nM		HDAC4, IC₅₀: 510 nM		HDAC6, IC₅₀: 14000 nM								99.98%
Valproic acid sodium	HDAC, IC₅₀: 0.5-2 mM	HDAC1, IC₅₀: 400 μM													99.65%
Tucidinostat		HDAC1, IC₅₀: 95 nM	HDAC2, IC₅₀: 160 nM	HDAC3, IC₅₀: 67 nM					HDAC8, IC₅₀: 733 nM		HDAC10, IC₅₀: 78 nM	HDAC11, IC₅₀: 432 nM			98.60%
RGFP966				HDAC3, IC₅₀: 80 nM											99.81%
Sodium butyrate	HDAC														99.67%
Belinostat	HDAC, IC₅₀: 27 nM (Hela cell)						HDAC6, IC₅₀: 82 nM								99.94%
Sodium 4-phenylbutyrate	HDAC														99.86%
Tubastatin A		HDAC1, IC₅₀: 16400 nM					HDAC6, IC₅₀: 15 nM		HDAC8, IC₅₀: 854 nM						99.07%
Ricolinostat		HDAC1, IC₅₀: 58 nM	HDAC2, IC₅₀: 48 nM	HDAC3, IC₅₀: 51 nM	HDAC4, IC₅₀: 7000 nM	HDAC5, IC₅₀: 5000 nM	HDAC6, IC₅₀: 4.7 nM	HDAC7, IC₅₀: 1400 nM	HDAC8, IC₅₀: 100 nM						99.83%
Tasquinimod					HDAC4, Kd: 10-30 nM										99.94%
ITSA-1	HDAC														99.73%
Mocetinostat		HDAC1, IC₅₀: 0.15 μM	HDAC2, IC₅₀: 0.29 μM	HDAC3, IC₅₀: 1.66 μM								HDAC11, IC₅₀: 0.59 μM			99.68%
Quisinostat		HDAC1, IC₅₀: 0.11 nM	HDAC2, IC₅₀: 0.33 nM	HDAC3, IC₅₀: 4.86 nM	HDAC4, IC₅₀: 0.64 nM	HDAC5, IC₅₀: 3.69 nM	HDAC6, IC₅₀: 76.8 nM	HDAC7, IC₅₀: 119 nM	HDAC8, IC₅₀: 4.26 nM	HDAC9, IC₅₀: 32.1 nM	HDAC10, IC₅₀: 0.46 nM	HDAC11, IC₅₀: 0.37 nM			99.71%
TMP195					HDAC4, IC₅₀: 111 nM	HDAC5, IC₅₀: 106 nM	HDAC6, IC₅₀: 47800 nM	HDAC7, IC₅₀: 46 nM	HDAC8, IC₅₀: 11700 nM	HDAC9, IC₅₀: 9 nM					99.82%
LMK-235		HDAC1, IC₅₀: 320 nM	HDAC2, IC₅₀: 881 nM		HDAC4, IC₅₀: 11.9 nM	HDAC5, IC₅₀: 4.22 nM	HDAC6, IC₅₀: 55.7 nM		HDAC8, IC₅₀: 1278 nM			HDAC11, IC₅₀: 852 nM			99.61%
Santacruzamate A			HDAC2, IC₅₀: 119 pM				HDAC6, IC₅₀: 434 nM								99.54%
Tubacin		HDAC1, IC₅₀: 1.40 μM	HDAC2, IC₅₀: 6.27 μM	HDAC3, IC₅₀: 1.27 μM	HDAC4, IC₅₀: 17.30 μM	HDAC5, IC₅₀: 3.35 μM	HDAC6, IC₅₀: 4 nM	HDAC7, IC₅₀: 9.70 μM	HDAC8, IC₅₀: 1.27 μM	HDAC9, IC₅₀: 4.31 μM	HDAC10, IC₅₀: 3.71 μM	HDAC11, IC₅₀: 3.79 μM			99.54%
PCI-34051		HDAC1, IC₅₀: 4 μM					HDAC6, IC₅₀: 2.9 μM		HDAC8, IC₅₀: 10 nM		HDAC10, IC₅₀: 13 μM				99.84%
Givinostat		hHDAC1, IC₅₀: 198 nM	hHDAC2, IC₅₀: 325 nM	hHDAC3, IC₅₀: 157 nM	hHDAC4, IC₅₀: 1059 nM	hHDAC5, IC₅₀: 532 nM	hHDAC6, IC₅₀: 315 nM	hHDAC7, IC₅₀: 524 nM	hHDAC8, IC₅₀: 854 nM	hHDAC9, IC₅₀: 541 nM	hHDAC10, IC₅₀: 340 nM	hHDAC11, IC₅₀: 292 nM	HD1-B, IC₅₀: 7.5 nM HD1-A, IC₅₀: 16 nM	HD2, IC₅₀: 10 nM	98.67%
Tubastatin A Hydrochloride		HDAC1, IC₅₀: 16400 nM					HDAC6, IC₅₀: 15 nM		HDAC8, IC₅₀: 854 nM						99.31%
Tacedinaline		HD1, IC₅₀: 0.9 μM	HD2, IC₅₀: 0.9 μM	HD3, IC₅₀: 1.2 μM											99.32%
Fimepinostat		HDAC1, IC₅₀: 1.7 nM	HDAC2, IC₅₀: 5 nM	HDAC3, IC₅₀: 1.8 nM	HDAC4, IC₅₀: 409 nM	HDAC5, IC₅₀: 674 nM	HDAC6, IC₅₀: 27 nM	HDAC7, IC₅₀: 426 nM	HDAC8, IC₅₀: 191 nM	HDAC9, IC₅₀: 554 nM	HDAC10, IC₅₀: 2.8 nM	HDAC11, IC₅₀: 5.4 nM			99.95%
Pyroxamide		HDAC1, ID₅₀: 100 nM													99.54%
TMP269					HDAC4, IC₅₀: 157 nM	HDAC5, IC₅₀: 97 nM	HDAC6, IC₅₀: 82000 nM	HDAC7, IC₅₀: 43 nM	HDAC8, IC₅₀: 42000 nM	HDAC9, IC₅₀: 23 nM					98.16%
Apicidin								HDAC7	HDAC8						99.87%
FT895												HDAC11, IC₅₀: 3 nM			99.84%
CUDC-101	HDAC, IC₅₀: 4.4 nM	HDAC1, IC₅₀: 4.5 nM	HDAC2, IC₅₀: 12.6 nM	HDAC3, IC₅₀: 9.1 nM	HDAC4, IC₅₀: 13.2 nM	HDAC5, IC₅₀: 11.4 nM	HDAC6, IC₅₀: 5.1 nM	HDAC7, IC₅₀: 373 nM	HDAC8, IC₅₀: 79.8 nM	HDAC9, IC₅₀: 67.2 nM	HDAC10, IC₅₀: 26.1 nM				99.05%
SIS17												HDAC11, IC₅₀: 0.83 μM			99.65%
Dacinostat	HDAC, IC₅₀: 32 nM	HDAC1, IC₅₀: 9 nM													98.45%
Pracinostat		HDAC1, IC₅₀: 49 nM	HDAC2, IC₅₀: 96 nM	HDAC3, IC₅₀: 43 nM	HDAC4, IC₅₀: 56 nM	HDAC5, IC₅₀: 47 nM	HDAC6, IC₅₀: 1008 nM	HDAC7, IC₅₀: 137 nM	HDAC8, IC₅₀: 140 nM	HDAC9, IC₅₀: 70 nM	HDAC10, IC₅₀: 40 nM	HDAC11, IC₅₀: 93 nM			99.80%
Abexinostat		HDAC1, Ki: 7 nM	HDAC2, Ki: 19 nM	HDAC3/SMRT, Ki: 8.2 nM			HDAC6, Ki: 17 nM		HDAC8, Ki: 280 nM		HDAC10, Ki: 24 nM				99.00%
M344	HDAC, IC₅₀: 100 nM														99.76%
Elevenostat												HDAC11, IC₅₀: 0.235 μM
Sinapinic acid	HDAC, IC₅₀: 2.27 mM														99.94%
CAY10603		HDAC1, IC₅₀: 271 nM	HDAC2, IC₅₀: 252 nM	HDAC3, IC₅₀: 0.42 nM			HDAC6, IC₅₀: 0.002 nM		HDAC8, IC₅₀: 6851 nM		HDAC10, IC₅₀: 90.7 nM				99.76%
ACY-738		HDAC1, IC₅₀: 94 nM	HDAC2, IC₅₀: 128 nM	HDAC3, IC₅₀: 218 nM			HDAC6, IC₅₀: 1.7 nM								99.92%
Butyric acid	HDAC														99.81%
RG2833		HDAC1, IC₅₀: 60 nM HDAC1, Ki: 32 nM		HDAC3, IC₅₀: 50 nM HDAC3, Ki: 5 nM											99.26%
1-Stearoyl-sn-glycero-3-phosphocholine				HDAC3											99.53%
Citarinostat		HDAC1, IC₅₀: 35 nM	HDAC2, IC₅₀: 45 nM	HDAC3, IC₅₀: 46 nM			HDAC6, IC₅₀: 2.6 nM	HDAC7, IC₅₀: 7300 nM	HDAC8, IC₅₀: 137 nM						98.66%
Nexturastat A		HDAC1, IC₅₀: 3.02 μM	HDAC2, IC₅₀: 6.92 μM	HDAC3, IC₅₀: 6.68 μM	HDAC4, IC₅₀: 9.39 μM	HDAC5, IC₅₀: 11.7 μM	HDAC6, IC₅₀: 5.02 nM	HDAC7, IC₅₀: 4.46 μM	HDAC8, IC₅₀: 0.954 μM	HDAC9, IC₅₀: 6.72 μM	HDAC10, IC₅₀: 7.57 μM	HDAC11, IC₅₀: 5.14 μM			98.28%
MC1568	HDAC
CYD19		HDAC1, IC₅₀: 0.405 μM													99.76%
TH34							HDAC6, IC₅₀: 4.6 μM		HDAC8, IC₅₀: 1.9 μM		HDAC10, IC₅₀: 7.7 μM				99.52%
BRD3308		HDAC1, IC₅₀: 1260 nM HDAC1, Ki: 5100 nM	HDAC2, IC₅₀: 1340 nM HDAC2, Ki: 6300 nM	HDAC3, IC₅₀: 54 nM HDAC3, Ki: 29 nM											98.34%
Quisinostat dihydrochloride		HDAC1, IC₅₀: 0.11 nM	HDAC2, IC₅₀: 0.33 nM	HDAC3, IC₅₀: 4.86 nM	HDAC4, IC₅₀: 0.64 nM	HDAC5, IC₅₀: 3.69 nM	HDAC6, IC₅₀: 76.8 nM	HDAC7, IC₅₀: 119 nM	HDAC8, IC₅₀: 4.26 nM	HDAC9, IC₅₀: 32.1 nM	HDAC10, IC₅₀: 0.46 nM	HDAC11, IC₅₀: 0.37 nM			99.05%
Givinostat hydrochloride monohydrate		hHDAC1, IC₅₀: 198 nM	hHDAC2, IC₅₀: 325 nM	hHDAC3, IC₅₀: 157 nM	hHDAC4, IC₅₀: 1059 nM	hHDAC5, IC₅₀: 532 nM	hHDAC6, IC₅₀: 315 nM	hHDAC7, IC₅₀: 524 nM	hHDAC8, IC₅₀: 854 nM	hHDAC9, IC₅₀: 541 nM	hHDAC10, IC₅₀: 340 nM	hHDAC11, IC₅₀: 292 nM	HD1-B, IC₅₀: 7.5 nM HD1-A, IC₅₀: 16 nM	HD2, IC₅₀: 10 nM	98.06%
Zabadinostat		HDAC1, IC₅₀: 63 nM	HDAC2, IC₅₀: 570 nM	HDAC3, IC₅₀: 550 nM											99.81%
TYA-018							HDAC6								99.84%
Bufexamac				HDAC3, Kd app: 341 μM			HDAC6, Kd app: 10.7 μM		HDAC8, Kd app: 235 μM		HDAC10, Kd app: 12.3 μM				≥98.0%
TNG260		HDAC1		HDAC3											99.91%
Scriptaid	HDAC														98.59%
BRD-6929		HDAC1, IC₅₀: 1 nM	HDAC2, IC₅₀: 8 nM	HDAC3, IC₅₀: 458 nM											≥99.0%
ACY-775		HDAC1, IC₅₀: 2123 nM	HDAC2, IC₅₀: 2570 nM	HDAC3, IC₅₀: 11223 nM			HDAC6, IC₅₀: 7.5 nM								99.71%
Crotonoside				HDAC3			HDAC6								99.46%
ACY-1083							HDAC6, IC₅₀: 3 nM								99.80%
HDAC8-IN-1									HDAC8, IC₅₀: 27.2 nM						99.77%
SR-4370		HDAC1, IC₅₀: 130 nM	HDAC2, IC₅₀: 580 nM	HDAC3, IC₅₀: 6 nM			HDAC6, IC₅₀: 3400 nM		HDAC8, IC₅₀: 2300 nM						98.38%
BRD 4354						HDAC5, IC₅₀: 0.85 μM				HDAC9, IC₅₀: 1.88 μM					98.10%
CHDI-390576		HDAC1, IC₅₀: 39.7 μM		HDAC3, IC₅₀: 25.8 μM	HDAC4, IC₅₀: 54 nM	HDAC5, IC₅₀: 60 nM	hHDAC6, IC₅₀: 6.2 μM	HDAC7, IC₅₀: 31 nM	HDAC8, IC₅₀: 9.1 μM	hHDAC9, IC₅₀: 50 nM					98.10%
ACY-957		HDAC1, IC₅₀: 7 nM	HDAC2, IC₅₀: 18 nM	HDAC3, IC₅₀: 1300 nM											99.66%
9-Hydroxyoctadecanoic acid		HDAC1													≥98.0%
HDAC10-IN-1							hHDAC6, IC₅₀: 2420 ± 530 nM		hHDAC8, IC₅₀: 920 ± 170 nM		HDAC10, IC₅₀: 58 ± 10 nM				99.87%
SW-100		HDAC1, IC₅₀: 5.23 μM	HDAC2, IC₅₀: 32.8 μM	HDAC3, IC₅₀: 29.5 μM	HDAC4, IC₅₀: 10.9 μM	HDAC5, IC₅₀: 4.07 μM	HDAC6, IC₅₀: 2.3 nM	HDAC7, IC₅₀: 4.55 μM	HDAC8, IC₅₀: 3.72 μM	HDAC9, IC₅₀: 3.46 μM	HDAC10, IC₅₀: 26.2 μM	HDAC11, IC₅₀: 5.72 μM			99.93%
KA2507							HDAC6, IC₅₀: 2.5 nM		HDAC8, IC₅₀: 621						99.24%
Nanatinostat	HDAC, IC₅₀: 8 nM	HDAC1, IC₅₀: 3 nM	HDAC2, IC₅₀: 4 nM	HDAC3, IC₅₀: 7 nM		HDAC5, IC₅₀: 200 nM	HDAC6, IC₅₀: 2100 nM								99.67%
Domatinostat		HDAC-1, IC₅₀: 1.2 μM	HDAC-2, IC₅₀: 1.12 μM	HDAC-3, IC₅₀: 0.57 μM		HDAC-5, IC₅₀: 11.3 μM				HDAC-9, IC₅₀: 50 μM	HDAC-10, IC₅₀: 21 μM	HDAC-11, IC₅₀: 9.7 μM			99.34%
HDAC3-IN-T247		HDAC1, IC₅₀: 19 μM		HDAC3, IC₅₀: 0.24 μM	HDAC4, IC₅₀: >100 μM		HDAC6, IC₅₀: >100 μM		HDAC8, IC₅₀: >100 μM						98.91%
Tinostamustine		HDAC1, IC₅₀: 9 nM	HDAC2, IC₅₀: 9 nM	HDAC3, IC₅₀: 25 nM			HDAC6, IC₅₀: 6 nM		HDAC8, IC₅₀: 107 nM		HDAC10, IC₅₀: 72 nM				99.64%
UF010			HDAC2, IC₅₀: 0.32 μM	HDAC3, IC₅₀: 256.7 nM			HDAC6, IC₅₀: 18.93 μM		HDAC8, IC₅₀: 3.97 μM						99.83%
T-518							hHDAC6, IC₅₀: 36 nM								98.40%
KR-39038						HDAC5									99.68%
Pimelic Diphenylamide 106		HDAC1, IC₅₀: 150 nM	HDAC2, IC₅₀: 760 nM	HDAC3, IC₅₀: 370 nM					HDAC8, IC₅₀: 5000 nM						98.54%
BML-210					HDAC4:MEF2										98.04%
Droxinostat				HDAC3, IC₅₀: 16.9 μM			HDAC6, IC₅₀: 2.47 μM		HDAC8, IC₅₀: 1.46 μM						98.91%
SS-208		HDAC1, IC₅₀: 1.39 μM				HDAC5, IC₅₀: 6.91 μM	HDAC6, IC₅₀: 12 nM	HDAC7, IC₅₀: 8.34 μM	HDAC8, IC₅₀: 1.23 μM			HDAC11, IC₅₀: 5.12 μM			99.00%
SE-7552							HDAC6, IC₅₀: 33 nM								99.48%
J22352							HDAC6, IC₅₀: 4.7 nM								99.04%
HDACs/mTOR Inhibitor 1		HDAC1, IC₅₀: 0.19 nM					HDAC6, IC₅₀: 1.8 nM								99.01%
Resminostat hydrochloride		HDAC1, IC₅₀: 42.5 nM		HDAC3, IC₅₀: 50.1 nM			HDAC6, IC₅₀: 71.8 nM		HDAC8, IC₅₀: 877 nM						99.68%
Crebinostat		HDAC1, IC₅₀: 0.7 nM	HDAC2, IC₅₀: 1.0 nM	HDAC3, IC₅₀: 2.0 nM			HDAC6, IC₅₀: 9.3 nM								99.79%
HPOB		HDAC1, IC₅₀: 2.9 μM	HDAC2, IC₅₀: 4.4 μM	HDAC3/NCOR2, IC₅₀: 1.7 μM			HDAC6, IC₅₀: 0.056 μM		HDAC8, IC₅₀: 2.8 μM		HDAC10, IC₅₀: 3.0 μM				99.80%
Suberoyl bis-hydroxamic acid		HDAC1, IC₅₀: 0.25 μM		HDAC3, IC₅₀: 0.30 μM											≥98.0%
Valproic acid (Standard)	HDAC, IC₅₀: 0.5-2 nM	HDAC1, IC₅₀: 400 μM
WT-161		HDAC1, IC₅₀: 8.35 nM	HDAC2, IC₅₀: 15.4 nM	HDAC3, IC₅₀: 51.6 nM			HDAC6, IC₅₀: 0.4 nM		HDAC8, IC₅₀: 1430 nM						98.36%
GSK3117391	HDAC														99.40%
LSD1/HDAC6-IN-2							HDAC6, IC₅₀: 11 nM								99.66%
PROTAC HDAC6 degrader 2							HDAC6, IC₅₀: 0.643 μM								99.80%
NT160					HDAC4, IC₅₀: 0.08 nM	HDAC5, IC₅₀: 1.2 nM		HDAC7, IC₅₀: 1.0 nM		HDAC9, IC₅₀: 0.9 nM					99.58%
Oxamflatin	HDAC, IC₅₀: 15.7 nM														98.13%
BRD6688			HDAC2												98.90%
Psammaplin A		HDAC1, IC₅₀: 45 nM
YX968				HDAC3, DC₅₀: 1.7 nM					HDAC8, DC₅₀: 6.8 nM						98.06%
Givinostat hydrochloride		hHDAC1, IC₅₀: 198 nM	hHDAC2, IC₅₀: 325 nM	hHDAC3, IC₅₀: 157 nM	hHDAC4, IC₅₀: 1059 nM	hHDAC5, IC₅₀: 532 nM	hHDAC6, IC₅₀: 315 nM	hHDAC7, IC₅₀: 524 nM	hHDAC8, IC₅₀: 854 nM	hHDAC9, IC₅₀: 541 nM	hHDAC10, IC₅₀: 340 nM	hHDAC11, IC₅₀: 292 nM	HD1-B, IC₅₀: 7.5 nM HD1-A, IC₅₀: 16 nM	HD2, IC₅₀: 10 nM	98.06%
BG45		HDAC1, IC₅₀: 2.0 μM	HDAC2, IC₅₀: 2.2 μM	HDAC3, IC₅₀: 0.289 μM			HDAC6, IC₅₀: >20 μM								99.95%
CG347B							HDAC6								98.07%
Domatinostat tosylate		HDAC-1, IC₅₀: 1.2 μM	HDAC-2, IC₅₀: 1.12 μM	HDAC-3, IC₅₀: 0.57 μM		HDAC-5, IC₅₀: 11.3 μM				HDAC-9, IC₅₀: 50 μM	HDAC-10, IC₅₀: 21 μM	HDAC-11, IC₅₀: 9.7 μM			99.66%
MPT0G211							HDAC6, IC₅₀: 0.291 μM								99.79%
HDAC6 degrader-3		HDAC1, IC₅₀: 0.647 μM					HDAC6, ID₅₀: 19.4 nM HDAC6, IC₅₀: 4.54 nM								98.60%
NCC-149									HDAC8						99.14%
Panobinostat lactate	HDAC														98.67%
Tefinostat	HDAC														99.65%
CM-675		HDAC1, IC₅₀: 673 nM (30 min (time-dependent))													99.53%
Ivaltinostat formic	HDAC														98.26%
NKL 22		HDAC1, IC₅₀: 0.199 μM	HDAC2, IC₅₀: 1.59 μM	HDAC3, IC₅₀: 0.069 μM					HDAC8, IC₅₀: 5 μM
BRD4884		HDAC1, IC₅₀: 29 nM	HDAC2, IC₅₀: 62 nM	HDAC3, IC₅₀: 1.09 μM											99.0%
SB-429201				HDAC3, IC₅₀: 1.5 μM											98.15%
Resminostat		HDAC1, IC₅₀: 42.5 nM		HDAC3, IC₅₀: 50.1 nM			HDAC6, IC₅₀: 71.8 nM		HDAC8, IC₅₀: 877 nM						99.84%
Imofinostat		HDAC1, IC₅₀: 53.0 nM	HDAC2, IC₅₀: 106.2 nM				HDAC6, IC₅₀: 29.5 nM		HDAC8, IC₅₀: 2532.6 nM						99.40%
Splitomicin	Sir2p, IC₅₀: 60 μM														98.42%
DNMT/HDAC-IN-1		HDAC1, IC₅₀: 56.84 nM					HDAC6, IC₅₀: 17.39 nM								99.87%
1-Naphthohydroxamic acid		HDAC1, IC₅₀: >100 μM					HDAC6, IC₅₀: >100 μM		HDAC8, IC₅₀: 14 μM						99.59%
MIR002												HDAC11, IC₅₀: 6.09 μM			≥99.0%
HDAC6 degrader-5		HDAC1, IC₅₀: 1240 nM					HDAC6, IC₅₀: 4.95 nM								99.55%
BRD2492		HDAC1, IC₅₀: 13.2 nM	HDAC2, IC₅₀: 77.2 nM	HDAC3, IC₅₀: 8908 nM			HDAC6, IC₅₀: >1000 nM								99.18%
GEM144												HDAC11, IC₅₀: 8.23 μM
AES-135				HDAC3, IC₅₀: 654 nM			HDAC6, IC₅₀: 190 nM		HDAC8, IC₅₀: 1100 nM			HDAC11, IC₅₀: 636 nM			98.21%
HDAC-IN-40			HDAC2, Ki: 60 nM		HDAC4, Ki: 49200 μM		HDAC6, Ki: 30 nM		HDAC8, Ki: 5690 nM						98.71%
Chlopynostat		HDAC1, IC₅₀: 67 nM													98.36%
MC1742		HDAC1, IC₅₀: 0.1 μM	HDAC2, IC₅₀: 0.11 μM	HDAC3, IC₅₀: 0.02 μM			HDAC6, IC₅₀: 0.007 μM		HDAC8, IC₅₀: 0.61 μM		HDAC10, IC₅₀: 0.04 μM	HDAC11, IC₅₀: 0.1 μM			98.95%
PTACH		HDAC1, IC₅₀: 48 nM			HDAC4, IC₅₀: 32 nM		HDAC6, IC₅₀: 41 nM								99.65%
KPZ560		HDAC1, IC₅₀: 12 nM	HDAC2, IC₅₀: 68 nM												99.72%
HD-TAC7		HDAC1, IC₅₀: 3.6 μM	HDAC2, IC₅₀: 4.2 μM	HDAC3, IC₅₀: 1.1 μM											98.75%
BG48		HDAC1	HDAC2
Bavarostat		HDAC1, IC₅₀: >1000 μM	HDAC2, IC₅₀: >1000 μM	HDAC3, IC₅₀: >1000 μM	HDAC4, IC₅₀: 11.3 μM	HDAC5, IC₅₀: 19 μM	HDAC6, IC₅₀: 0.06 μM	HDAC7, IC₅₀: 4.7 μM	HDAC8, IC₅₀: 8.5 μM	HDAC9, IC₅₀: 5.2 μM		HDAC11, IC₅₀: 10 μM			99.51%
Purinostat		HDAC1	HDAC2
BRD73954			HDAC2, IC₅₀: 9 μM				HDAC6, IC₅₀: 0.036 μM		HDAC8, IC₅₀: 0.12 μM						98.0%
BRD 4354 ditrifluoroacetate						HDAC5, IC₅₀: 0.85 μM				HDAC9, IC₅₀: 1.88 μM					98.06%
Purinostat mesylate		HDAC1, IC₅₀: 0.81 nM	HDAC2, IC₅₀: 1.4 nM	HDAC3, IC₅₀: 1.7 nM	HDAC4, IC₅₀: 1072 nM	HDAC5, IC₅₀: 426 nM	HDAC6, IC₅₀: 11.5 nM	HDAC7, IC₅₀: 590 nM	HDAC8, IC₅₀: 3.8 nM	HDAC9, IC₅₀: 622 nM	HDAC10, IC₅₀: 1.1 nM	HDAC11, IC₅₀: 3349 nM			99.45%
PH14				HDAC3, IC₅₀: 24.5 nM											99.29%
HPB		HDAC1, IC₅₀: 1130 nM					HDAC6, IC₅₀: 31 nM								99.11%
Pomiferin	HDAC, IC₅₀: 1.05 μM														98.98%
cis-BG47		HDAC1	HDAC2												98.02%
CARM1/HDAC2-IN-1			HDAC2, IC₅₀: 4.07 nM
HDAC6-IN-33							HDAC6, IC₅₀: 193 nM								98.96%
PROTAC HDAC degrader-2							hHDAC6, DC₅₀: 13 nM				hHDAC10, DC₅₀: 29 nM
HDAC1-IN-7		HDAC1, IC₅₀: 0.957 mM													99.97%
HDAC9-IN-1										HDAC9, IC₅₀: 40 nM
HDAC11-IN-2									HDAC8, IC₅₀: 5 μM			HDAC11, IC₅₀: 0.0511 μM			99.52%
SelSA		HDAC1, IC₅₀: 6.41 μM					HDAC6, IC₅₀: 0.0569 μM		HDAC8, IC₅₀: 7.32 μM						99.83%
HDAC8-IN-8		hHDAC1, IC₅₀: 12.1 μM					hHDAC6, IC₅₀: 2.9 μM		hHDAC8, IC₅₀: 23.9 μM smHDAC8, IC₅₀: 268.2 μM						99.01%
Ivaltinostat	HDAC
AES-350				HDAC3, IC₅₀: 187 nM			HDAC6, IC₅₀: 24.4 nM					HDAC11, IC₅₀: 245 nM			99.30%
FNDR-20123	human HDAC, IC₅₀: 3 nM Plasmodium HDAC, IC₅₀: 31 nM	HDAC1, IC₅₀: 25 nM	HDAC2, IC₅₀: 29 nM	HDAC3, IC₅₀: 2 nM			HDAC6, IC₅₀: 11 nM		HDAC8, IC₅₀: 282 nM						98.08%
JNJ-16241199		HDAC1, IC₅₀: 3.3 nM							HDAC8, IC₅₀: 23 nM						99.05%
Tucidinostat-d₄		HDAC1, IC₅₀: 95 nM	HDAC2, IC₅₀: 160 nM	HDAC3, IC₅₀: 67 nM							HDAC10, IC₅₀: 78 nM				98.63%
Pivanex	HDAC
HDAC6-IN-13		HDAC1, IC₅₀: 1.53 μM	HDAC2, IC₅₀: 2.06 μM	HDAC3, IC₅₀: 1.03 μM			HDAC6, IC₅₀: 0.019 μM								98.08%
BRD9757		HDAC1, IC₅₀: 0.638 μM	HDAC2, IC₅₀: 1.79 μM	HDAC3, IC₅₀: 0.694 μM	HDAC4, IC₅₀: 21.80 μM	HDAC5, IC₅₀: 18.32 μM	HDAC6, IC₅₀: 0.03 μM	HDAC7, IC₅₀: 12.61 μM	HDAC8, IC₅₀: 1.09 μM	HDAC9, IC₅₀: >33.33 μM					99.75%
TO-1187							HDAC6, DC₅₀: 5.81 nM
QTX125 TFA							HDAC6								99.93%
QTX125							HDAC6
CRA-026440 hydrochloride		HDAC1, IC₅₀: 4 nM	HDAC2, IC₅₀: 14 nM	HDAC3/SMRT, IC₅₀: 11 nM			HDAC6, IC₅₀: 15 nM		HDAC8, IC₅₀: 7 nM		HDAC10, IC₅₀: 20 nM				98.12%
JAK/HDAC-IN-1	HDAC, IC₅₀: 2 nM		HDAC2, IC₅₀: 14 nM				HDAC6, IC₅₀: 120 nM		HDAC8, IC₅₀: 2470 nM						98.63%
HDAC-IN-53		HDAC1, IC₅₀: 47 nM	HDAC2, IC₅₀: 125 nM	HDAC3, IC₅₀: 450 nM	HDAC4, IC₅₀: >10 μM	HDAC5, IC₅₀: >10 μM	HDAC6, IC₅₀: >10 μM	HDAC7, IC₅₀: >10 μM	HDAC8, IC₅₀: >10 μM	HDAC9, IC₅₀: >10 μM
SIRT6-IN-3				HDAC3, IC₅₀: 111.9 μM			HDAC6, IC₅₀: 96.77 μM		HDAC8, IC₅₀: 102 μM						98.19%
MOCPAC		HDAC1													99.64%
HDAC6-IN-46							HDAC6, IC₅₀: 6.2 nM								98.51%
HDAC-IN-52		hHDAC1, IC₅₀: 0.189 μM	hHDAC2, IC₅₀: 0.227 μM	hHDAC3, IC₅₀: 0.440 μM							hHDAC10, IC₅₀: 0.446 μM				99.46%
HDAC-IN-27 dihydrochloride		HDAC1, IC₅₀: 3.01 nM	HDAC2, IC₅₀: 18.54 nM	HDAC3, IC₅₀: 0.435 nM											≥99.0%
SHP2/HDAC-IN-1		HDAC1, IC₅₀: 25 nM	HDAC2, IC₅₀: 79 nM	HDAC3, IC₅₀: 233 nM			HDAC6, IC₅₀: 27 nM
MPT0G211 mesylate							HDAC6, IC₅₀: 0.291 μM
HDAC6-IN-5	HDAC, IC₅₀: 0.16 ± 0.0 μM	HDAC1, IC₅₀: 0.09 ± 0.0 μM	HDAC2, IC₅₀: 0.48 ± 0.0 μM	HDAC3, IC₅₀: 0.33 ± 0. μM	HDAC4, IC₅₀: 7.85 ± 0.6 μM	HDAC5, IC₅₀: 7.19 ± 0.4 μM	HDAC6, IC₅₀: 0.026 ± 0. μM	HDAC7, IC₅₀: 9.13 ± 0.3 μM		HDAC9, IC₅₀: 5.51 ± 0.0 μM
FNDR-20123 free base	human HDAC, IC₅₀: 3 nM Plasmodium HDAC, IC₅₀: 31 nM	HDAC1, IC₅₀: 25 nM	HDAC2, IC₅₀: 29 nM	HDAC3, IC₅₀: 2 nM			HDAC6, IC₅₀: 11 nM		HDAC8, IC₅₀: 282 nM
ROCK/HDAC-IN-2							HDAC6, IC₅₀: 0.185 μM
SZUH280									HDAC8, DC₅₀: 0.58 μM						99.38%
LSD1/HDAC6-IN-1							HDAC6
PI3K/HDAC-IN-1		HDAC1, IC₅₀: 1.4 nM	HDAC2, IC₅₀: 3.0 nM				HDAC6, IC₅₀: 6.6 nM		HDAC8, IC₅₀: 18 nM
HDAC1/2 and CDK2-IN-1		HDAC1, IC₅₀: 70.7 nM	HDAC2, IC₅₀: 23.1 nM
HDAC6-IN-6	HDAC, IC₅₀: 0.55 ± 0.0 μM	HDAC1, IC₅₀: 0.34 ± 0.0 μM	HDAC2, IC₅₀: 1.57 ± 0.0 μM	HDAC3, IC₅₀: 1.22 ± 0.0 μM	HDAC4, IC₅₀: 2.24 ± 0.0 μM	HDAC5, IC₅₀: 0.85 ± 0.0 μM	HDAC6, IC₅₀: 0.025 ± 0. μM	HDAC7, IC₅₀: 0.65 ± 0.0 μM		HDAC9, IC₅₀: 0.57 ± 0.0 μM
DNMT1/HDAC-IN-1		HDAC1, IC₅₀: 0.05 μM
HDAC6-IN-27							HDAC6, IC₅₀: 15.9 nM HDAC6, IC₅₀: 6180.2 nM		HDAC8, IC₅₀: 136.5 nM
ZG-126		HDAC1, IC₅₀: 2.53 μM	HDAC2, IC₅₀: 4.64 μM	HDAC3, IC₅₀: 0.997 μM	HDAC4, IC₅₀: 67.6 μM	HDAC5, IC₅₀: 59.4 μM	HDAC6, IC₅₀: 0.633 μM	HDAC7, IC₅₀: 55.4 μM	HDAC8, IC₅₀: 3.31 μM		HDAC10, IC₅₀: 13.9 μM	HDAC11, IC₅₀: 2.02 μM
LSQ-28				HDAC3, IC₅₀: 42 nM
HDAC6-IN-38		HDAC1, IC₅₀: 20.5 nM					HDAC6, IC₅₀: 3.11 nM
PB200							HDAC6, IC₅₀: 1.97 nM
HDAC-IN-45		HDAC1, IC₅₀: 0.108 μM	HDAC2, IC₅₀: 0.585 μM	HDAC3, IC₅₀: 0.563 μM μM			HDAC6, IC₅₀: ﹥10 μM		HDAC8, IC₅₀: 6.81 μM
GSK-3β/HDAC-IN-2		HDAC1, Ki: 0.036 μM	HDAC2, Ki: 0.070 μM HDAC2, IC₅₀: 1.05 μM	HDAC3, Ki: 0.066 μM			HDAC6, Ki: 0.017 μM HDAC6, IC₅₀: 1.52 μM		HDAC8, Ki: 0.772 μM
HDAC-IN-38		HDAC1, IC₅₀: 3.82 μM	HDAC2, IC₅₀: 6.62 μM	HDAC3, IC₅₀: 2.86 μM		HDAC5, IC₅₀: 6.27 μM	HDAC6, IC₅₀: 1.27 μM		HDAC8, IC₅₀: 0.533 μM
HDAC-IN-79		HDAC1, IC₅₀: 134 nM	HDAC2, IC₅₀: 284 nM	HDAC3, IC₅₀: 173 nM			HDAC6, IC₅₀: 1.32 nM
PD-L1/HDAC6-IN-1		HDAC1, IC₅₀: 9.08 μM					HDAC6, IC₅₀: 69 nM
HDAC-IN-72		HDAC1, IC₅₀: 0.65 μM	HDAC2, IC₅₀: 0.78 μM	HDAC3, IC₅₀: 1.70 μM
HDAC1-IN-5		HDAC1, IC₅₀: 15 nM					HDAC6, IC₅₀: 20 nM
HDAC-IN-50		HDAC1, IC₅₀: 1.3 nM	HDAC2, IC₅₀: 1.6 nM				HDAC6, IC₅₀: 2.6 nM		HDAC8, IC₅₀: 13 nM
1-Stearoyl-sn-glycero-3-phosphocholine-d₃₅				HDAC3
HDAC3-IN-1		HDAC1, IC₅₀: 36.4 ± 0.2 nM	HDAC2, IC₅₀: 89.9 ± 0.7 nM	HDAC3, IC₅₀: 5.96 ± 0.0 nM
PI3Kδ/HDAC6-IN-1							HDAC6, IC₅₀: 6.2 nM
TD034												HDAC11, IC₅₀: 5.1 nM HDAC11, Ki: 1.5 nM
HDAC6-IN-10		HDAC1, IC₅₀: 8020 nM			HDAC4, IC₅₀: 5620 nM	HDAC5, IC₅₀: 4370 nM	HDAC6, IC₅₀: 0.73 nM	HDAC7, IC₅₀: 752 nM	HDAC8, IC₅₀: 513 nM	HDAC9, IC₅₀: 2560 nM	HDAC10, IC₅₀: 105 nM	HDAC11, IC₅₀: 1800 nM
HDAC-IN-51		HDAC1, IC₅₀: 0.353 μM	HDAC2, IC₅₀: 0.431 μM	HDAC3, IC₅₀: 0.515 μM							HDAC10, IC₅₀: 0.32 μM	HDAC11, IC₅₀: 85.4 μM
HDAC6/HSP90-IN-2		HDAC1, IC₅₀: 654.5 nM		HDAC3, IC₅₀: 1539 nM			HDAC6, IC₅₀: 106 nM	HDAC7, IC₅₀: 1691 nM
HDAC3/6-IN-2		HDAC1, IC₅₀: 2.512 μM	HDAC2, IC₅₀: 4.830 μM	HDAC3, IC₅₀: 0.635 μM			HDAC6, IC₅₀: 0.368 μM
CYP17A1/HDAC6-IN-1							HDAC6, IC₅₀: 0.6015 μM
LSD1/HDAC-IN-3		HDAC1, IC₅₀: 1702 nM	HDAC2, IC₅₀: 842 nM	HDAC3, IC₅₀: 358 nM
HDAC2-IN-1		HDAC1, IC₅₀: 1.61 μM	HDAC2, IC₅₀: 0.5 μM						HDAC8, IC₅₀: 0.98 μM
MC2590		HDAC1, IC₅₀: 0.098 μM	HDAC2, IC₅₀: 0.156 μM	HDAC3, IC₅₀: 0.039 μM	HDAC4, IC₅₀: 2.73 μM	HDAC5, IC₅₀: 1.35 μM	HDAC6, IC₅₀: 0.015 μM	HDAC7, IC₅₀: 2.06 μM	HDAC8, IC₅₀: 0.047 μM	HDAC9, IC₅₀: 2.79 μM	HDAC10, IC₅₀: 0.071 μM	HDAC11, IC₅₀: 3.98 μM			98.71%
ITF5924							HDAC6, IC₅₀: 7.7 nM
HDAC-IN-36		HDAC1, IC₅₀: 86.93 nM	HDAC2, IC₅₀: 97.32 nM	HDAC3, IC₅₀: 79.17 nM	HDAC4, IC₅₀: >1000 nM	HDAC5, IC₅₀: >1000 nM	HDAC6, IC₅₀: 11.68 nM	HDAC7, IC₅₀: >1000 nM	HDAC8, IC₅₀: 378.2 nM	HDAC9, IC₅₀: >1000 nM	HDAC10, IC₅₀: 13.24 nM	HDAC11, IC₅₀: >1000 nM
HDAC6-IN-42							HDAC6, IC₅₀: 0.009 μM
Tubulin/HDAC-IN-4		HDAC1, IC₅₀: 0.73 μM	HDAC2, IC₅₀: 0.43 μM				HDAC6, IC₅₀: 0.62 μM	HDAC7, IC₅₀: 2.34 μM
HDAC1-IN-6		HDAC1, IC₅₀: 1.9±0.3 μM	HDAC2, IC₅₀: >30 μM				HDAC6, IC₅₀: >30 μM					HDAC11, IC₅₀: 1.6±0.3 μM
HDAC6 degrader-4							HDAC6
HDAC-IN-34		HDAC1, IC₅₀: 0.022 ± 0. μM					HDAC6, IC₅₀: 0.45 ± 0.0 μM
HDAC-IN-42		HDAC1, IC₅₀: 0.19 μM					HDAC6, IC₅₀: 4.98 μM
Naph-Se-TMZ		HDAC1
HDAC8-IN-6					HDAC4, IC₅₀: 23.1 μM				HDAC8, IC₅₀: 5.1 μM
LSD1/HDAC-IN-1		HDAC1, IC₅₀: 0.125 nM	HDAC2, IC₅₀: 0.373 nM				HDAC6, IC₅₀: 0.0118 nM		HDAC8, IC₅₀: 0.103 nM
HDAC-IN-74	HDAC, IC₅₀: 10.8 μM
HDAC1/CDK7-IN-1		HDAC1, IC₅₀: 248 nM
HDAC3-IN-3				HDAC3
c-Met/HDAC-IN-3		HDAC1, IC₅₀: 26.97 nM
HDAC6-IN-15							HDAC6, IC₅₀: 38.2 nM
HDAC6/HSP90-IN-3							HDAC6, IC₅₀: 28 nM
PARP-1/HDAC-IN-1			HDAC2, IC₅₀: 42130 nM	HDAC3, IC₅₀: 7220 nM			HDAC6, IC₅₀: 510 nM
PROTAC HDAC6 degrader 5		hHDAC1, IC₅₀: 162 nM							hHDAC8, IC₅₀: 864 nM		hHDAC10, IC₅₀: 2447 nM
PI3K/HDAC-IN-2		HDAC1, IC₅₀: 1.3 nM	HDAC2, IC₅₀: 3.4 nM		HDAC4, IC₅₀: 972 nM		HDAC6, IC₅₀: 17 nM		HDAC8, IC₅₀: 12 nM
NMDAR/HDAC-IN-1		HDAC1, IC₅₀: 2.67 μM	HDAC2, IC₅₀: 8.00 μM	HDAC3, IC₅₀: 2.21 μM			HDAC6, IC₅₀: 0.18 μM		HDAC8, IC₅₀: 0.62 μM
NB512		HDAC1, EC₅₀: 0.11 μM	HDAC2, EC₅₀: 0.1 μM	HDAC3, EC₅₀: 13.6 μM
c-Met/HDAC-IN-2		HDAC1, IC₅₀: 18.49 nM
HDAC3-IN-6		HDAC1, IC₅₀: 3.98 μM		HDAC3, IC₅₀: 53 nM
HDAC8/BRPF1-IN-1									hHDAC8, IC₅₀: 443 nM
PHD2/HDACs-IN-1		HDAC1, IC₅₀: 19.75 μM	HDAC2, IC₅₀: 26.60 μM				HDAC6, IC₅₀: 15.98 μM
HDAC/CK2-IN-1		HDAC1, IC₅₀: 1.46 μM					HDAC6, IC₅₀: 0.66 μM
Tubulin/HDAC-IN-3		HDAC1, IC₅₀: 0.155 ± 0. μM					HDAC6, IC₅₀: 1.037 ± 0. μM		HDAC8, IC₅₀: 0.177 ± 0. μM
HDAC6-IN-45		HDAC1, IC₅₀: 28.2 μM	HDAC2, IC₅₀: 19.3 μM	HDAC3, IC₅₀: 13.6 μM			HDAC6, IC₅₀: 15.2 nM
HDAC-IN-49		HDAC1, IC₅₀: 13 nM	HDAC2, IC₅₀: 14 nM	HDAC3, IC₅₀: 21 nM	HDAC4, IC₅₀: 1880 nM		HDAC6, IC₅₀: 10 nM
1-Alaninechlamydocin	HDAC, IC₅₀: 6.4 nM
HDAC1/MAO-B-IN-1		HDAC1, IC₅₀: 21.4 nM
TH-6		HDAC1, IC₅₀: 0.115 μM	HDAC2, IC₅₀: 0.135 μM	HDAC3, IC₅₀: 0.242 μM			HDAC6, IC₅₀: 0.138 μM		HDAC8, IC₅₀: 2.120 μM
NN-390		HDAC1, IC₅₀: >5 μM	HDAC2, IC₅₀: >5 μM	HDAC3, IC₅₀: >1 μM			HDAC6, IC₅₀: 9.8 nM		HDAC8, IC₅₀: >1 μM			HDAC11, IC₅₀: >1 μM
HDAC10-IN-2							hHDAC6, IC₅₀: 3700 ± 450 nM		hHDAC8, IC₅₀: 470 ± 70 nM		HDAC10, IC₅₀: 20 ± 2 nM
mTOR/HDAC-IN-1		HDAC1, IC₅₀: 0.91 nM					HDAC6, IC₅₀: 86 nM		HDAC8, IC₅₀: 27 nM
HDACs/EZH2-IN-1		HDAC1, IC₅₀: 0.23 μM			HDAC4, IC₅₀: >10 μM		HDAC6, IC₅₀: 0.07 μM					HDAC11, IC₅₀: >10 μM
HDAC/Top-IN-1		HDAC1, IC₅₀: 34 nM	HDAC2, IC₅₀: 140 nM	HDAC3, IC₅₀: 59 nM			HDAC6, IC₅₀: 89 nM		HDAC8, IC₅₀: 9.8 μM
VEGFR2/HDAC1-IN-1	HDAC, IC₅₀: 9.82 nM
HDAC6-IN-53							HDAC6, IC₅₀: 19.65 nM
HDAC6/8/BRPF1-IN-1		HDAC1, IC₅₀: 797 nM					HDAC6, IC₅₀: 344 nM		HDAC8, IC₅₀: 908 nM
HDAC-IN-9		HDAC1, IC₅₀: 6.8 μM	HDAC2, IC₅₀: 0.06 μM				HDAC6, IC₅₀: 0.12 μM		HDAC8, IC₅₀: 8.5 μM
HDAC6-IN-43		HDAC1, IC₅₀: 111 ± 5 nM	HDAC2, IC₅₀: 105 ± 5 nM				HDAC6, IC₅₀: 11 ± 1 nM		HDAC8, IC₅₀: 15404 ± 99 nM
HDAC-IN-76		hHDAC1, IC₅₀: 7 nM					hHDAC6, IC₅₀: 9 nM
HDAC-IN-73		HDAC1, IC₅₀: 0.17 μM					HDAC6, IC₅₀: 0.49 μM
HDAC-IN-71		HDAC1, IC₅₀: 12.6 nM	HDAC2, IC₅₀: 14.1 nM	HDAC3, IC₅₀: 20 nM			HDAC6, IC₅₀: 3 nM				HDAC10, IC₅₀: 72 nM
Trichostatin C		HDAC1					HDAC6
ZWZH-21		HDAC1, IC₅₀: 34 nM	HDAC2, IC₅₀: 41 nM	HDAC3, IC₅₀: 277 nM			HDAC6, IC₅₀: >800 nM		HDAC8, IC₅₀: >800
HDAC1/6-IN-3		HDAC1, IC₅₀: 1.1 nM					HDAC6, IC₅₀: 2.7 nM
IOR-160		HDAC1, IC₅₀: 3.3 nM	HDAC2, IC₅₀: 24 nM	HDAC3, IC₅₀: 3.9 nM			HDAC6, IC₅₀: 13 nM
HDAC-IN-31		HDAC1, IC₅₀: 84.90 nM	HDAC2, IC₅₀: 168.0 nM	HDAC3, IC₅₀: 442.7 nM					HDAC8, IC₅₀: >10000 nM
AAK1/HDACs-IN-1		HDAC1, IC₅₀: 148.6 nM					HDAC6, IC₅₀: 5.2 nM
JAK/HDAC-IN-2	HDAC, IC₅₀: 170 nM	HDAC1, IC₅₀: 340 nM	HDAC2, IC₅₀: 303 nM	HDAC3, IC₅₀: 58.7 nM	HDAC4, IC₅₀: >10000 nM	HDAC5, IC₅₀: >10000 nM	HDAC6, IC₅₀: 4.44 nM	HDAC7, IC₅₀: >10000 nM	HDAC8, IC₅₀: >10000 nM	HDAC9, IC₅₀: >10000 nM	HDAC10, IC₅₀: 116.1 nM	HDAC11, IC₅₀: 724.4 nM
KH-259		HDAC1, IC₅₀: 6.7 ± 0.14 μM			HDAC4, IC₅₀: 12.3 ± 0.4 μM		HDAC6, IC₅₀: 0.26 ± 0.2 μM
HDAC-IN-91		HDAC1, IC₅₀: 134.22 nM	HDAC2, IC₅₀: 66.29 nM
Temozolomide-amino hydrochloride		HDAC1
EGFR/HDAC-IN-2				HDAC3, IC₅₀: 1.09 nM
ZINC000028464438												HDAC11, IC₅₀: 3.5 μM
PIM-1/HDAC-IN-2		HDAC1, IC₅₀: 41 nM	HDAC2, IC₅₀: 341 nM	HDAC3, IC₅₀: 101 nM	HDAC4, IC₅₀: 3456 nM	HDAC5, IC₅₀: 379 nM	HDAC6, IC₅₀: 8 nM	HDAC7, IC₅₀: 690 nM	HDAC8, IC₅₀: 225 nM	HDAC9, IC₅₀: 1084 nM	HDAC10, IC₅₀: 72 nM	HDAC11, IC₅₀: 105 nM
HDSI-18							HDAC6, IC₅₀: 1.6 nM
HDAC6-IN-35							HDAC6, IC₅₀: 4.7 μM
HDAC-IN-75		HDAC1, IC₅₀: 1352 nM					HDAC6, IC₅₀: 6.32 nM
HDAC-IN-81		HDAC1, IC₅₀: 4.5 nM
HDAC11-IN-1												HDAC11, Ki: 40 nM
Chlamydocin	HDAC, IC₅₀: 1.3 nM
HDAC-IN-69														HD2
ALK/HDAC-IN-1		HDAC1, IC₅₀: 10.8 μM					HDAC6, IC₅₀: 1.03 μM		HDAC8, IC₅₀: 1.69 μM			HDAC11, IC₅₀: 16.6 μM
HDAC6-IN-36		HDAC1, IC₅₀: 1284 nM					HDAC6, IC₅₀: 8.64 nM
Coumarin-SAHA									HDAC8
MC2625		HDAC1, IC₅₀: 1.42 μM	HDAC2, IC₅₀: 1.77 μM	HDAC3, IC₅₀: 80 nM	HDAC4, IC₅₀: 11.7 μM	HDAC5, IC₅₀: 9.37 μM	HDAC6, IC₅₀: 11 nM	HDAC7, IC₅₀: 8.77 μM	HDAC8, IC₅₀: 0.61 μM	HDAC9, IC₅₀: 10.6 μM	HDAC10, IC₅₀: 1.8 μM	HDAC11, IC₅₀: 10.2 μM
PROTAC HDAC6 degrader 4		HDAC1, IC₅₀: 2.2 μM	HDAC2, IC₅₀: 2.37 μM	HDAC3, IC₅₀: 0.611 μM			HDAC6, DC₅₀: 14 nM HDAC6, IC₅₀: 0.295 μM
HDAC-IN-39		HDAC1, IC₅₀: 1.07 μM	HDAC2, IC₅₀: 1.47 μM	HDAC3, IC₅₀: 2.27 μM					HDAC8, IC₅₀: >10 μM
AChE/HDAC-IN-1	HDAC, IC₅₀: 0.23 nM
HDAC6-IN-44		HDAC1, IC₅₀: 878 nM	HDAC2, IC₅₀: 3144 nM		HDAC4, IC₅₀: 847 nM		HDAC6, IC₅₀: 8.97 nM HDAC6, IC₅₀: 8.97 nM	HDAC7, IC₅₀: 894 nM			HDAC10, IC₅₀: 1319 nM	HDAC11, IC₅₀: >5000 nM
HDAC6-IN-59							HDAC6, IC₅₀: 3.12 nM
Nanatinostat TFA	HDAC, IC₅₀: 8 nM	HDAC1, IC₅₀: 3 nM	HDAC2, IC₅₀: 4 nM	HDAC3, IC₅₀: 7 nM		HDAC5, IC₅₀: 200 nM	HDAC6, IC₅₀: 2100 nM
HDAC3-IN-7				HDAC3, IC₅₀: 311 nM
PI3K/HDAC-IN-4		HDAC1, IC₅₀: 75.5 nM	HDAC2, IC₅₀: 70.9 nM	HDAC3, IC₅₀: 1.9 nM
HDAC/PSMD14-IN-1		HDAC1, IC₅₀: 141.2 nM
HDAC-IN-67		HDAC1, IC₅₀: 22 nM					HDAC6, IC₅₀: 8 nM
HDAC8-IN-2		hHDAC1, IC₅₀: 18.51 ± 1. μM					hHDAC6, IC₅₀: 0.29 ± 0.0 μM		hHDAC8, IC₅₀: 0.32 ± 0.0 μM
HDAC-IN-46		HDAC1, IC₅₀: 0.21 μM					HDAC6, IC₅₀: 0.021 μM
HDAC-IN-57		HDAC1, IC₅₀: 2.07 nM	HDAC2, IC₅₀: 4.71 nM				HDAC6, IC₅₀: 2.4 nM		HDAC8, IC₅₀: 107 nM
LT-630							HDAC6
DS-103		HDAC1, IC₅₀: 0.029 μM	HDAC2, IC₅₀: 0.123 μM	HDAC3, IC₅₀: 0.022 μM			HDAC6, IC₅₀: 0.367 μM		HDAC8, IC₅₀: 9.26 μM
EGFR/HDAC-IN-1		HDAC1, IC₅₀: 119.4 nM		HDAC3, IC₅₀: 354.8 nM
LASSBio-1911							HDAC6
HDAC6-IN-34		HDAC1, IC₅₀: 3.91 μM					HDAC6, IC₅₀: 18 nM
CM-444		HDAC1, IC₅₀: 6.55 nM	HDAC2, IC₅₀: 51 nM	HDAC3, IC₅₀: 18 nM	HDAC4, IC₅₀: 62 nM	HDAC5, IC₅₀: 59 nM	HDAC6, IC₅₀: 531 nM	HDAC7, IC₅₀: 120 nM	HDAC8, IC₅₀: 83 nM	HDAC9, IC₅₀: 90 nM	HDAC10, IC₅₀: 15 nM	HDAC11, IC₅₀: 567.5 nM
J208		HDAC1
HDAC-IN-41		HDAC1, IC₅₀: 0.62 μM	HDAC2, IC₅₀: 1.46 μM	HDAC3, IC₅₀: 0.62 μM
M122		HDAC1, IC₅₀: 0.48 μM	hHDAC2, IC₅₀: 0.47 μM
HDAC-IN-89		HDAC1, IC₅₀: 0.95 nM	HDAC2, IC₅₀: 0.86 nM	HDAC3, IC₅₀: 1.06 nM			HDAC6, IC₅₀: >1000 nM		HDAC8, IC₅₀: 4.24 nM
PROTAC HDAC6 degrader 6							HDAC6
FF2039		HDAC1, IC₅₀: 1.03 μM	HDAC2, IC₅₀: 2.15 μM		HDAC4, IC₅₀: 12.4 μM		HDAC6, IC₅₀: 0.053 μM
HDAC1-IN-8		HDAC1, IC₅₀: 11.94 μM					HDAC6, IC₅₀: 22.95 μM		HDAC8, IC₅₀: >500 μM
HDAC4-IN-1			HDAC2, IC₅₀: 6.13 μM		HDAC4, IC₅₀: 0.012 μM		HDAC6, IC₅₀: 5.79 μM		HDAC8, IC₅₀: 4.26 μM
PTG-0861							HDAC6, IC₅₀: 5.92 nM
HDAC-IN-47		HDAC1, IC₅₀: 19.75 nM	HDAC2, IC₅₀: 57.8 nM	HDAC3, IC₅₀: 40.27 nM			HDAC6, IC₅₀: 5.63 nM		HDAC8, IC₅₀: 302.73 nM
HDAC6-IN-47		HDAC1, Ki: 60 nM	HDAC2, Ki: 56 nM	HDAC3, Ki: 162 nM			HDAC6, Ki: 0.44 nM		HDAC8, Ki: 362 nM		HDAC10, Ki: 849 nM
HDAC1-IN-9		HDAC1, IC₅₀: 1.07 μM
HDAC1-IN-3		HDAC1, IC₅₀: 2.2 nM	HDAC2, IC₅₀: 5.1 nM	HDAC3, IC₅₀: 5.2 nM			HDAC6, IC₅₀: 85.5 nM		HDAC8, IC₅₀: 29.9 nM
NR160							HDAC6, IC₅₀: 30 nM
HDAC6-IN-50							HDAC6, IC₅₀: 35 nM
HDAC6-IN-4		HDAC1, IC₅₀: 3604 nM	HDAC2, IC₅₀: 172 nM	HDAC3, IC₅₀: 46 nM			HDAC6, IC₅₀: 23 nM		HDAC8, IC₅₀: 2175 nM
HDAC8-IN-4				HDAC3, IC₅₀: 12 μM					HDAC8, IC₅₀: 0.15 μM
HDAC6-IN-48		HDAC1, IC₅₀: 638.08 nM		HDAC3, IC₅₀: 396.72 nM			HDAC6, IC₅₀: 5.16 nM
HDAC6-IN-41							HDAC6, IC₅₀: 30 nM		HDAC8, IC₅₀: 422 nM
XSJ-10		HDAC1, IC₅₀: 11.37 nM	HDAC2, IC₅₀: 9.97 nM	HDAC3, IC₅₀: 8.97 nM	HDAC4, IC₅₀: 75.05 nM	HDAC5, IC₅₀: 75.14 nM	HDAC6, IC₅₀: 67.04 nM	HDAC7, IC₅₀: 121.28 nM	HDAC8, IC₅₀: 88.64 nM	HDAC9, IC₅₀: 83.67 nM	HDAC10, IC₅₀: 77.55 nM	HDAC11, IC₅₀: 72.54 nM
HDAC6-IN-14		HDAC1, IC₅₀: 8.01 μM	HDAC2, IC₅₀: 4.48 μM	HDAC3, IC₅₀: 8.35 μM	HDAC4, IC₅₀: >10 μM		HDAC6, IC₅₀: 42 nM
(S)-Trichostatin A		hHDAC1, IC₅₀: 206.3 nM	hHDAC2, IC₅₀: 612.65 nM	hHDAC3, IC₅₀: 320.8 nM	hHDAC4, IC₅₀: 6341 nM	hHDAC5, IC₅₀: 6325 nM	hHDAC6, IC₅₀: 11.1 nM Zebrafish HDAC6, IC₅₀: 9.88 nM	hHDAC7, IC₅₀: 1823.5 nM	hHDAC8, IC₅₀: 312.2 nM	hHDAC9, IC₅₀: 4824 nM	hHDAC10, IC₅₀: 403.35 nM	hHDAC11, IC₅₀: 2684 nM
TNI-97		HDAC1, IC₅₀: 2890 nM	HDAC2, IC₅₀: 1306 nM	HDAC3, IC₅₀: 3177 nM	HDAC4, IC₅₀: >5000 nM	HDAC5, IC₅₀: >5000 nM	HDAC6, IC₅₀: 0.2 nM	HDAC7, IC₅₀: >5000 nM	HDAC8, IC₅₀: 4130 nM	HDAC9, IC₅₀: >5000 nM	HDAC10, IC₅₀: 3162 nM	HDAC11, IC₅₀: >5000 nM
HDAC8-IN-3		HDAC1, IC₅₀: ＞50 μM	HDAC2, IC₅₀: 41 μM	HDAC3, IC₅₀: ＞50 μM	HDAC4, IC₅₀: ＞50 μM	HDAC5, IC₅₀: ＞50 μM	HDAC6, IC₅₀: 17 μM		HDAC8, IC₅₀: 9.3 μM HDAC8, IC₅₀: ＞50 μM
HDAC6-IN-17					HDAC4, IC₅₀: 2300 nM		HDAC6, IC₅₀: 150 nM		HDAC8, IC₅₀: 1400 nM
HDAC-IN-84		HDAC1, IC₅₀: 0.0045 μM	HDAC2, IC₅₀: 0.015 μM	HDAC-3, IC₅₀: 0.013 μM	HDAC4, IC₅₀: >100 μM		HDAC6, IC₅₀: 0.038 μM		HDAC8, IC₅₀: 5.8 μM			HDAC11, IC₅₀: 26 μM
Top/HDAC-IN-2		HDAC1, IC₅₀: 0.004 μM	HDAC2, IC₅₀: 0.005 μM	HDAC3, IC₅₀: 1.10 μM			HDAC6, IC₅₀: 0.15 μM		HDAC8, IC₅₀: 4.5 μM
Valproic acid sodium (2:1)	HDAC, IC₅₀: 0.5-2 mM	HDAC1, IC₅₀: 400 μM
LSD1/HDAC-IN-2		HDAC1, IC₅₀: 1.4 nM	HDAC2, IC₅₀: 1.0 nM	HDAC3, IC₅₀: 1.3 nM			HDAC6, IC₅₀: 2.9 nM		HDAC8, IC₅₀: 16.0 nM
HDAC6-IN-31		HDAC1, IC₅₀: 3.07 μM					HDAC6, IC₅₀: 0.026 μM
PIM-1/HDAC-IN-1	HDAC, IC₅₀: 65.94 ± 3. nM	HDAC1, IC₅₀: 63.65 ± 3. nM	HDAC2, IC₅₀: 132.62 nM	HDAC3, IC₅₀: 323.02 nM	HDAC4, IC₅₀: 265.47 nM		HDAC6, IC₅₀: 62.39 ± 3. nM		HDAC8, IC₅₀: 406.66 nM
PROTAC HDAC6 degrader 1		HDAC1, IC₅₀: 0.1 μM					HDAC6, DC₅₀: 3.5 nM HDAC6, IC₅₀: 4.86 nM
HDAC6-IN-52							HDAC6
HDAC6-IN-60							HDAC6
HDAC-IN-88		HDAC1, IC₅₀: 1.103 μM	HDAC2, IC₅₀: 2.308 μM	HDAC3, IC₅₀: 3.864 μM			HDAC6, IC₅₀: 0.226 μM		HDAC8, IC₅₀: 3.255 μM
HDAC/HSP90-IN-3	HDAC, IC₅₀: 0.91 μM (fungal HDACs) human HDAC, IC₅₀: 3.0 μM (human HDACs)
HDAC-IN-35		HDAC1, IC₅₀: 7.23 μM					HDAC6, IC₅₀: 0.166 μM		HDAC8, IC₅₀: 1.99 μM
SAHA-OH		HDAC1, IC₅₀: 237 nM	HDAC2, IC₅₀: 399 nM	HDAC3, IC₅₀: 359 nM			HDAC6, IC₅₀: 23 nM		HDAC8, IC₅₀: 1070 nM
A2AAR/HDAC-IN-1		HDAC1, IC₅₀: 145.3 ± 12 nM	HDAC2, IC₅₀: 240.2 ± 19 nM	HDAC3, IC₅₀: 443.5 ± 27 nM			HDAC6, IC₅₀: >10000 nM		HDAC8, IC₅₀: >10000 nM
HDAC6-IN-54							HDAC6, IC₅₀: 0.021 μM
CDK9/HDAC1/HDAC3-IN-1		HDAC1, IC₅₀: 1.73 μM		HDAC3, IC₅₀: 1.11 μM
HDAC-IN-43		HDAC1, IC₅₀: 82 nM	HDAC2, IC₅₀: 358 nM	HDAC3, IC₅₀: 45 nM			HDAC6, IC₅₀: 24 nM		HDAC8, IC₅₀: 1441 nM		HDAC10, IC₅₀: 182 nM	HDAC11, IC₅₀: 9061 nM
HDAC6-IN-61		HDAC1, IC₅₀: 1310 nM	HDAC2, IC₅₀: 2353 nM	HDAC3, IC₅₀: 626 nM		HDAC5, IC₅₀: 73 nM	HDAC6, IC₅₀: 73 nM		HDAC8, IC₅₀: 2413 nM
NL-103		HDAC1, IC₅₀: 21.3 nM	HDAC2, IC₅₀: 57 nM	HDAC3, IC₅₀: 74 nM			HDAC6, IC₅₀: 680 nM
sEH/HDAC6-IN-2		HDAC1, IC₅₀: 1.151 μM	HDAC2, IC₅₀: 0.492 μM	HDAC3, IC₅₀: 1.276 μM			HDAC6, IC₅₀: 0.008 μM		HDAC8, IC₅₀: 0.062 μM			HDAC11, IC₅₀: 0.464 μM
mTOR/HDAC6-IN-1							HDAC6, IC₅₀: 56 nM
HDAC6-IN-58							HDAC6, IC₅₀: 9.5 nM
HDAC3-IN-4		HDAC1, IC₅₀: 730 nM		HDAC3, IC₅₀: 89 nM			HDAC6, IC₅₀: >10 μM	HDAC7, IC₅₀: >10 μM	HDAC8, IC₅₀: >10 μM
sEH/HDAC6-IN-1		HDAC1, IC₅₀: 0.2731 μM	HDAC2, IC₅₀: 0.8 μM	HDAC3, IC₅₀: 0.49 μM			HDAC6, IC₅₀: 5 nM					HDAC11, IC₅₀: 0.3142 μM
GSK-3β/HDAC-IN-1			HDAC2, IC₅₀: 0.03 μM				HDAC6, IC₅₀: 0.045 μM
PDE5/HDAC-IN-1		HDAC1, IC₅₀: 2.45 μM					HDAC6, IC₅₀: 0.11 μM		HDAC8, IC₅₀: 0.12 μM
CDK/HDAC-IN-2		HDAC1, IC₅₀: 6.4 nM	HDAC2, IC₅₀: 0.25 nM	HDAC3, IC₅₀: 45 nM			HDAC6, IC₅₀: >1000 nM		HDAC8, IC₅₀: >1000 nM
HDAC1/6-IN-1		HDAC1, IC₅₀: 89 nM					HDAC6, IC₅₀: 13 nM
C1A		HDAC1, IC₅₀: 14 μM	HDAC2, IC₅₀: 11 μM	HDAC3, IC₅₀: 5.5 μM	HDAC4, IC₅₀: 16 μM	HDAC5, IC₅₀: 15 μM	HDAC6, IC₅₀: 0.48 μM	HDAC7, IC₅₀: 49 μM	HDAC8, IC₅₀: 0.61 μM	HDAC9, IC₅₀: 56 μM	HDAC10, IC₅₀: 9.8 μM
HDAC-IN-27		HDAC1, IC₅₀: 3.01 nM	HDAC2, IC₅₀: 18.54 nM	HDAC3, IC₅₀: 0.435 nM
Fibrostat							HDAC6, IC₅₀: 63 nM
ROCK/HDAC-IN-1		HDAC1, IC₅₀: 9.09 nM	HDAC2, IC₅₀: 8.03 nM	HDAC3, IC₅₀: 6.26 nM			HDAC6, IC₅₀: 0.41 nM		HDAC8, IC₅₀: 7.69 nM
HDAC6-IN-11							HDAC6, IC₅₀: 20.7 nM		HDAC8, IC₅₀: 7750 nM
HDAC1/6-IN-2		HDAC1, IC₅₀: 3.1 nM					HDAC6, IC₅₀: 2.95 nM
HDAC6-IN-49		HDAC1, IC₅₀: 0.735 μM					HDAC6, IC₅₀: 0.012 μM
HDAC-IN-56		HDAC1, IC₅₀: 56.0 nM	HDAC2, IC₅₀: 90.0 nM	HDAC3, IC₅₀: 422.2 nM
HDAC3-IN-5		HDAC1, IC₅₀: 298.2 nM	HDAC2, IC₅₀: 1629 nM	HDAC3, IC₅₀: 4.2 nM
HDAC6/HSP90-IN-1		HDAC1, IC₅₀: 1878 nM		HDAC3, IC₅₀: 1312 nM			HDAC6, IC₅₀: 4.32 nM		HDAC8, IC₅₀: 3720 nM
Tubulin/HDAC-IN-1							HDAC6, IC₅₀: 1 μM		HDAC8, IC₅₀: 150 nM			HDAC11, IC₅₀: 1.9 μM
HDAC6-IN-62		HDAC1, IC₅₀: 1220 nM					HDAC6, IC₅₀: 0.25 nM
HDAC-IN-37		HDAC1, IC₅₀: 55.1 nM		HDAC3, IC₅₀: 1.24 μM			HDAC6, IC₅₀: 34.2 μM		HDAC8, IC₅₀: 0.948 μM
HR488B		HDAC1
G4/HDAC-IN-1		HDAC1, IC₅₀: 1.26 μM			HDAC4, IC₅₀: 2.64 μM		HDAC6, IC₅₀: 0.65 μM		HDAC8, IC₅₀: 0.03 μM			HDAC11, IC₅₀: 1.38 μM
HDAC8-IN-10									HDAC8, IC₅₀: 7.6 nM
DLC-50		HDAC1, IC₅₀: 31 nM
HDAC3/8 ligand-1				HDAC3					hHDAC8
HDAC-IN-68 hydrochloride	HDAC, IC₅₀: 0.04 μM
HDAC6-IN-9		HDAC1, IC₅₀: 11.8 nM		HDAC3, IC₅₀: 15.2 nM			HDAC6, IC₅₀: 4.2 nM		HDAC8, IC₅₀: 139.6 nM		HDAC10, IC₅₀: 21.3 nM
Leuxinostat		hHDAC1, IC₅₀: 1.203 μM		hHDAC3, IC₅₀: 2.858 μM			hHDAC6, IC₅₀: 0.03 μM		hHDAC8, IC₅₀: 2.446 μM		hHDAC10, IC₅₀: 4.811 μM	hHDAC11, IC₅₀: 5.57 μM
HDAC-IN-30		HDAC1, IC₅₀: 13.4 nM	HDAC2, IC₅₀: 28.0 nM	HDAC3, IC₅₀: 9.18 nM			HDAC6, IC₅₀: 42.7 nM		HDAC8, IC₅₀: 131 nM
HDAC6-IN-51			HDAC2, IC₅₀: 642.1 nM	HDAC3, IC₅₀: 1135.9 nM			HDAC6, IC₅₀: 42.9 nM		HDAC8, IC₅₀: 333.4 nM
HDAC11-IN-3												HDAC11, IC₅₀: 4.1 nM
J1075									HDAC8
HDAC6-IN-39							HDAC6, IC₅₀: 0.0096 μM
ZYJ-34c							HDAC6, IC₅₀: 0.056 μM		HDAC8, IC₅₀: 0.146 μM
ZYJ-25e							HDAC6, IC₅₀: 0.047 μM		HDAC8, IC₅₀: 0.139 μM
CM-545		HDAC1, pIC₅₀: 6.65	HDAC2, pIC₅₀: 6.14	HDAC3, pIC₅₀: 6.55			HDAC6, pIC₅₀: 6.84
BG47		HDAC1	HDAC2
TW9		HDAC1, IC₅₀: 0.29 μM
CHDI-00484077		HDAC1, IC₅₀: 17 μM	HDAC2, IC₅₀: 27 μM	HDAC3, IC₅₀: 10 μM	HDAC4, IC₅₀: 0.01 μM	HDAC5, IC₅₀: 0.02 μM	HDAC6, IC₅₀: 22 μM	HDAC7, IC₅₀: 0.02 μM	HDAC8, IC₅₀: 2.0 μM	HDAC9, IC₅₀: 0.03 μM
HDAC6-IN-40							HDAC6, IC₅₀: 0.029 μM
PD-L1/HDAC-IN-1			HDAC2, IC₅₀: 27.98 nM	HDAC3, IC₅₀: 14.47 nM
CRA-026440		HDAC1, Ki: 4 nM	HDAC2, Ki: 14 nM	HDAC3, Ki: 11 nM			HDAC6, Ki: 15 nM		HDAC8, Ki: 7 nM		HDAC10, Ki: 20 nM
IDO1 and HDAC1 Inhibitor		HDAC1, IC₅₀: 66.5 nM

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