2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. ATX inhibitor 11

ATX inhibitor 11 (compound 13c) 是一种有效的 ATX (autotaxin) 抑制剂，其 IC50 为 2.7 nM。在小鼠纤维化模型中，ATX inhibitor 11 可缓解纤维化组织的严重程度，有效减少纤维化生物标志物 α-SMA 的沉积。ATX inhibitor 11 可用于肺纤维化研究。

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ATX inhibitor 11 Chemical Structure

ATX inhibitor 11 Chemical Structure

CAS No. : 2485779-27-7

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ATX inhibitor 11 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

ATX inhibitor 11 (compound 13c) is a potent ATX (autotaxin) inhibitor, with an IC50 of 2.7 nM. ATX inhibitor 11 can typically alleviate the severity of fibrosis tissues and effectively reduce the deposition of fibrotic biomarker α-SMA in mice fibrosis model. ATX inhibitor 11 can be used for lung fibrosis research[1].

IC50 & Target

Autotaxin

2.7 ± 1 nM (IC50)

分子量

585.65

Formula

C32H35N5O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

ATX inhibitor 11 相关分类

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Keywords:

ATX inhibitor 112485779-27-7ATX inhibitor11ATX inhibitor-11Phosphodiesterase (PDE)Imidazo[1,2-a]pyridineLung fibrosisAutotaxinPhosphodiesteraseENPPHistological sectionsInhibitorinhibitorinhibit

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