1. Others Anti-infection Metabolic Enzyme/Protease
  2. Isotope-Labeled Compounds HCV Protease HCV SARS-CoV
  3. Boceprevir-d9

Boceprevir-d9  (Synonyms: EBP 520-d9; SCH 503034-d9)

目录号: HY-10237S
产品使用指南

Boceprevir-d9 是 Boceprevir 的氘代物。Boceprevir (EBP 520) 是一种口服有效的选择性的 HCV NS3 protease 抑制剂,酶实验中Ki 为 14 nM,在含细胞体系的复制实验中,EC90 为 350 nM。Boceprevir 抑制 SARS-CoV-2 3CLpro 活性。

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Boceprevir-d<sub>9</sub> Chemical Structure

Boceprevir-d9 Chemical Structure

CAS No. : 1256751-11-7

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规格 是否有货
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100 mg   询价  
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Other Forms of Boceprevir-d9:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Boceprevir-d9 is the deuterium labeled Boceprevir. Boceprevir (EBP 520) is a potent, highly selective, orally bioavailable HCV NS3 protease inhibitor with a Ki of 14 nM in both enzyme assay and an EC90 of 350 nM in cell-based replicon assay[1][2][3][4][5]. Boceprevir inhibits SARS-CoV-2 3CLpro activity[6].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

528.73

Formula

C27H36D9N5O5

CAS 号
非标记 CAS

394730-60-0

中文名称

波普瑞韦 d9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Boceprevir-d9
目录号:
HY-10237S
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