1. 天然产物
  2. 疾病研究领域 植物 食品研发 酚类
  3. 其他科 炎症/免疫
  4. 春榆
  5. Catechin 7-O-β-D-glucopyranoside

Catechin 7-O-β-D-glucopyranoside 

目录号: HY-N10587 纯度: ≥99.0%
COA 产品使用指南

Catechin 7-O-beta-D-glucopyranoside 是一种具有口服活性天然产物,发现于 Ulmus davidiana 和 Paeonia obovata。Catechin 7-O-beta-D-glucopyranoside 具有抗氧化和抗炎活性,并可减轻线粒体功能障碍,可用于肠道炎症性疾病的研究。

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Catechin 7-O-β-D-glucopyranoside Chemical Structure

Catechin 7-O-β-D-glucopyranoside Chemical Structure

CAS No. : 65597-47-9

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10 mg ¥1900
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Catechin 7-O-beta-D-glucopyranoside is an orally active natural product found in Ulmus davidiana and Paeonia obovata. Catechin 7-O-β-D-glucopyranoside shows antioxidant and anti-inflammatory activities, and attenuates mitochondrial dysfunction. Catechin 7-O-beta-D-glucopyranoside can be used in intestinal inflammatory disease research[1][2][3].

体外研究
(In Vitro)

Catechin 7-O-β-D-glucopyranoside (10 μg/mL; 24 h) shows protective effect against Streptozotocin-induced cell damage by its antioxidant effects and the attenuation of mitochondrial dysfunction[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[3]

Cell Line: RINm5F rat pancreatic β-cells
Concentration: 10 μg/mL
Incubation Time: 24 hours
Result: Increased the MnSOD level attenuated by Streptozotocin treatment.
Restored the Streptozotocin-induced reduction in mitochondrial CAT level.
体内研究
(In Vivo)

Catechin 7-O-β-D-glucopyranoside (intraperitoneal injection; 10 mg/kg; once) treatment shows mild protective effect against lethality induced by LPS/D-GalN[1].
Catechin 7-O-β-D-glucopyranoside (oral administration; 10 mg/kg; once daily; 7 d) treatment prevents intestinal inflammatory damages in TNBS model of rat colitis[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice injected with LPS/D-GalN[1]
Dosage: 10 mg/kg
Administration: Intraperitoneal injection; 10 mg/kg; once
Result: Showed 80% LPS/DGalN-induced lethality in mice.
Animal Model: Rat model of trinitrobenzenesulfonic acid (TNBS)-induced colitis [2]
Dosage: 10 mg/kg
Administration: Oral administration; 10 mg/kg; once daily; 7 days
Result: Suppressed body weight loss and intestinal inflammatory damages in TNBS-induced colitic rats.
Reduced myeloperoxidase activity and malondialdehyde level, but increased glutathione level in the TNBS colitic rats.
分子量

452.41

Formula

C21H24O11

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥99.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Catechin 7-O-β-D-glucopyranoside
目录号:
HY-N10587
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