2. Others Metabolic Enzyme/Protease NF-κB Anti-infection
  3. Biochemical Assay Reagents Endogenous Metabolite NF-κB Fungal
  4. Chitin, from crab carapace (powder),biomedical research grade

Chitin, from crab carapace (powder),biomedical research grade  (Synonyms: 几丁质,来源于蟹壳)

目录号: HY-126389
COA 产品使用指南 技术支持

Chitin, from crab carapace (powder),biomedical research grade 是N-乙酰葡萄糖胺以 β-(1-4) 键连接的长链聚合物。Chitin, from crab carapace (powder),biomedical research grade 存在于螃蟹的外骨骼中。Chitin, from crab carapace (powder),biomedical research grade 抑制 NF-κB p65 的激活、改变 NF-κB p65 向细胞核的转位、与念珠菌属细胞壁相互作用。Chitin, from crab carapace (powder),biomedical research grade 发挥抗真菌 (antifungal) 和抗炎作用。Chitin, from crab carapace (powder),biomedical research grade 主要用于胃溃疡和念珠菌病的研究。

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Chitin, from crab carapace (powder),biomedical research grade

Chitin, from crab carapace (powder),biomedical research grade Chemical Structure

CAS No. : 1398-61-4

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25 g ￥285
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50 g ￥420
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Other Forms of Chitin, from crab carapace (powder),biomedical research grade:

Chitin, from crab carapace (powder),biomedical research grade 相关抗体

Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Chitin, from crab carapace is a long-chain polymer of N-acetylglucosamine with β-(1-4) linkages. Chitin, from crab carapace is found in the exoskeleton of crabs. Chitin, from crab carapace inhibits the activation of NF-κB p65, alters the translocation of NF-κB p65 to the nucleus, and interacts with the cell wall of Candida species. Chitin, from crab carapace exerts antifungal and anti-inflammatory effects. Chitin, from crab carapace can be used in the research of gastric ulcer and candidiasis[1][2].

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Chitin, from crab carapace (powder),biomedical research grade 对 20 种临床分离的念珠菌表现出抗真菌活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Chitin, from crab carapace (powder),biomedical research grade 相关抗体:
体内研究
(In Vivo)

Chitin, from crab carapace (powder),biomedical research grade (150-600 mg/kg BW；13 天) 在乙醇诱导的胃溃疡 Wistar 大鼠模型中显著降低胃溃疡指数百分比并抑制 NF-κB p65 表达[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Wistar rats (10-12 weeks old, 190-210 g) with Ethanol-induced gastric ulcer[2]
Dosage: 150, 300, 600 mg/kg
Administration: 13 days
Result: Decreased necrotic cells and fat degeneration, and increased normal cells in gastric mucosa.
CAS 号
性状

固体

颜色

White to light yellow

中文名称

几丁质,来源于蟹壳； 甲壳素,来源于蟹壳； 壳多糖,来源于蟹壳
初始来源

Holotrichia parallela
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

COA (256 KB)

产品使用指南 (1538 KB)
参考文献

Chitin, from crab carapace (powder),biomedical research grade 相关分类

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Keywords:

Chitin, from crab carapace (powder),biomedical research grade1398-61-4几丁质,来源于蟹壳 甲壳素,来源于蟹壳 壳多糖,来源于蟹壳Biochemical Assay ReagentsEndogenous MetaboliteNF-κBFungalNuclear factor-κBNuclear factor-kappaBbiochemical assayWistar ratgastric ulcermantifungalCandidaInhibitorinhibitorinhibit

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