1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. TRP Channel
  3. D-erythro-Sphingosine hydrochloride

D-erythro-Sphingosine hydrochloride  (Synonyms: 盐酸鞘氨醇; Erythrosphingosine hydrochloride; erythro-C18-Sphingosine hydrochloride; trans-4-Sphingenine hydrochloride)

目录号: HY-W089922 纯度: ≥97.0%
COA 产品使用指南

D-erythro-Sphingosine (Erythrosphingosine) hydrochloride 是一种特异性 TRPM3 活化剂。D-erythro-Sphingosine 还诱导视网膜母细胞瘤蛋白 (retinoblastoma protein) 去磷酸化。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

D-erythro-Sphingosine hydrochloride Chemical Structure

D-erythro-Sphingosine hydrochloride Chemical Structure

CAS No. : 2673-72-5

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
25 mg ¥1100
In-stock
50 mg ¥1800
In-stock
100 mg   询价  
200 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of D-erythro-Sphingosine hydrochloride:

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

D-erythro-Sphingosine (Erythrosphingosine) hydrochloride is a specific TRPM3 activator. D-erythro-Sphingosine also induces retinoblastoma protein dephosphorylation[1][2].

IC50 & Target[1][2]

TRPM3

 

Retinoblastoma protein

 

体外研究
(In Vitro)

Extracellular application of D-erythro-Sphingosine (20 μM) induces an increase in [Ca2+]i in TRPM3-transfected HEK293 cells within 20 to 30 s after start of application, whereas nontransfected control cells (NT) shows only very small responses[1].
D-erythro-Sphingosine (10 μM) induces currents through TRPM3[1].
Induction of retinoblastoma protein dephosphorylation by D-erythro-Sphingosine (500 nM; 24 h) precede inhibition of growth and a specific arrest in the G0/G1 phase of the cell cycle[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

335.95

Formula

C18H38ClNO2

CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸D-赤式鞘氨醇;盐酸D-赤型神经胺;盐酸D-鞘氨醇;盐酸鞘氨醇;盐酸D-神经鞘氨醇

初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥97.0%

参考文献

D-erythro-Sphingosine hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
D-erythro-Sphingosine hydrochloride
目录号:
HY-W089922
需求量: