2. Apoptosis
  3. Apoptosis
  4. D-α-Tocopherol Succinate

D-α-Tocopherol Succinate  (Synonyms: Vitamin E succinate)

目录号: HY-131553 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

D-α-Tocopherol Succinate (Vitamin E succinate) 是一种抗氧化生育酚，是维生素 E 的一种盐形式。D-α-Tocopherol Succinat 抑制 Cisplatin (HY-17394) 引起的毒性。D-α-Tocopherol Succinate 可用于癌症的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

D-α-Tocopherol Succinate Chemical Structure

D-α-Tocopherol Succinate Chemical Structure

CAS No. : 4345-03-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
100 mg ￥400
In-stock
250 mg ￥600
In-stock
500 mg ￥760
In-stock
1 g   询价  
5 g   询价  

* Please select Quantity before adding items.

Customer Review

D-α-Tocopherol Succinate 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

D-α-Tocopherol Succinate (Vitamin E succinate) is an antioxidant tocopherol and a salt form of vitamin E. D-α-Tocopherol Succinate inhibits Cisplatin (HY-17394)-induced cytotoxicity. D-α-Tocopherol Succinate can be used for the research of cancer[1][2].

体外研究
(In Vitro)

D-α-Tocopherol Succinate (1-20 μM; 24 hours) shows cytotoxicity to HEI-OC1 cells[1].
D-α-Tocopherol Succinate (10 μM; 48 hours) protects HEI-OC1 cells against cisplatin-induced ototoxicity and inhibits caspase-3 activity[1].
D-α-Tocopherol Succinate (0-50 μM; 18 hours) shows cytotoxicity to TC-1 tumor cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

D-α-Tocopherol Succinate 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: HEI-OC1 cell line
Concentration: 1-20 μM
Incubation Time: 24 hours
Result: Significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxicity potency compared with 10 μM.

Cell Viability Assay[1]

Cell Line: HEI-OC1 cell line
Concentration: 10 μM
Incubation Time: 48 hours
Result: Increased cisplatin-induced cell population. Inhibited cisplatin-induced necrotic, ROS production and late apoptosis. Decreased cleaved PARP and inhibited the expression of caspase-3 which related to cisplatin-induced apoptosis.

Cell Cytotoxicity Assay[2]

Cell Line: TC-1 tumor cells
Concentration: 0, 25 and 50 μM
Incubation Time: 18 hours
Result: Dose-dependently showed cytotoxic and induced a higher percentage of necrotic TC-1 cells as opposed to apoptotic cells.
体内研究
(In Vivo)

D-α-Tocopherol Succinate (1-2 mg/kg; i.p. three times at 2 day intervals from TC-1 tumor cells injection for 10 days to 14 days) shows antitumor effects to mice with TC-1 tumor[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Six- to eight-week-old female C57BL/6 mice with TC-1 tumor cells[2]
Dosage: 1 and 2 mg/kg
Administration: Intraperitoneal injection; 1 and 2 mg/kg three times at 2 day intervals; from TC-1 tumor cells injection for 10 days to 14 days
Result: Dreased the tumor volume, especially with a dose of 2 mg/kg.
分子量

530.78

Formula

C33H54O5
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 250 mg/mL (471.00 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.8840 mL 9.4201 mL 18.8402 mL
5 mM 0.3768 mL 1.8840 mL 3.7680 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

D-α-Tocopherol Succinate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8840 mL 9.4201 mL 18.8402 mL 47.1005 mL
5 mM 0.3768 mL 1.8840 mL 3.7680 mL 9.4201 mL
10 mM 0.1884 mL 0.9420 mL 1.8840 mL 4.7100 mL
15 mM 0.1256 mL 0.6280 mL 1.2560 mL 3.1400 mL
20 mM 0.0942 mL 0.4710 mL 0.9420 mL 2.3550 mL
25 mM 0.0754 mL 0.3768 mL 0.7536 mL 1.8840 mL
30 mM 0.0628 mL 0.3140 mL 0.6280 mL 1.5700 mL
40 mM 0.0471 mL 0.2355 mL 0.4710 mL 1.1775 mL
50 mM 0.0377 mL 0.1884 mL 0.3768 mL 0.9420 mL
60 mM 0.0314 mL 0.1570 mL 0.3140 mL 0.7850 mL
80 mM 0.0236 mL 0.1178 mL 0.2355 mL 0.5888 mL
100 mM 0.0188 mL 0.0942 mL 0.1884 mL 0.4710 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-α-Tocopherol4345-03-3Vitamin EApoptosiscisplatinantioxidantototoxicityROSapoptosisTC-1HEI-OC1caspase-3Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
D-α-Tocopherol Succinate
目录号：
HY-131553
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z